Amplatzer Septal Occluder

Congenital heart disease (CHD) occurs in approximately 25 000 births per year in the United States. An atrial septal defect (ASD) is a spedfic form of CHD and is the third most common type of defect. Many people suffer from this disorder and in many cases it is only detected when the patient reaches middle age. Effective and efficient methods of repair are therefore needed to minimize the risks associated with traditional methods of ASD repair. In recent years, transcatheter closure methods for secundum type ASD have been developed. Currently the Amplatzer Septal Occluder, the Gore Helex Septal Occluder and the NMT Medical CardioSEAL-STARFiex Septal Occlusion systems have received FDA approval for ASD repair, the first of these only in 2001. This indicates that the use of these devices is still in its infancy. It can therefore be assumed that much more can be done to develop improved and more effective closure devices. It is the purpose of this chapter to describe ASDs and to outline the available technology with regard to transcatheter ASD repair devices. Hie discussion will centre around their construction and functioning, with special reference to their textile component. 

The Amplatzer Septal Occluder, produced by AGA Medical Corporation, Golden Valley, Minnesota was the first transcatheter device to be approved... 

Image of the Amplatzer Septal Occluder device used to repair secundum ASD. ... 

Amplatzer Septal Occluder Nitinol with polyester nonwoven Small to large Secundum ASD (maximum = larger than 20 mm) Self-centering device Stent-like... 

Garay F, Cao Q and Hijazi ZM. The Amplatzer septal occluder. In S. I D. Brecker,ed.Percaffl eoai Device Closure of the Atrial Septum.CmleA Kingdom Informa Heathcare 2006. 

Fu Y, Cao Q and Hijazi ZM. Closure of secundum atrial septal defect using the amplatzer septal occluder. In H. Sievert, S. A. Qureshi, N. Wilson, Z. M. Hijazi, eds. Percutaneous Interventions for Congenital Heart Disease. London Informa UK Ltd. 2007. 

Masura J, Gavora P and Podnar T. Long-term outcome of transcatheter secundum-type atrial septal defect closure using amplatzer septal occluders. J Am Coll Cardiol 2005 2/15 45(4) 505-507. 

Amplatzer Septal Occluder, 543 schematic diagram, 544 structure, 545 Anaconda device, 662-3 stent graft, 455,663 AneuRx device, 651-3 Talent stent graft, 652,653 two-component AneuRx bifurcated AAA stent graft, 652 aneurysm, 437 risk estimation, 644 anterior cruciate ligament anatomy and structure, 591-5 anteromedial and posterolateral bundles, 593... 

The original clamshell device was first introduced in 1989. It consisted of a double umbrella composed of four stainless steel arms covered with a polyester (Dacron ) meshwork. Each arm had a single springed hinge (see Fig. IS.S). - At the time of its introduction, double-umbrella devices were attractive because they offered the potential for minimal blood-flow pattern distortion due to their low profile. Additionally, since they possessed low alloy content, their corrosive potential was minimal. This device was deployed using an IIF sheath, which was smaller than the sheaths used by other devices at the time, but larger than those employed by the current Amplatzer Septal Occluder. ... 

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