Cineole, Percentage

Chymosin (Aspergillus niger var. awamori, Escherichia coli K-12, and Kluyveromyces marxianus, each microorganism containing a calf prochymosin gene), 786, (S3)20 Chymotrypsin, 786, (S3)18 Chymotrypsin Activity, 793 Cinene, 518 1,8-Cineol, 496 Cineole, Percentage of, 818 Cinnamal, 468 Cinnamaldehyde, 468, 611 Cinnamic Acid, 468, 565, 612, (S3)66 Cinnamic Alcohol, 470 Cinnamic Aldehyde, 468 Cinnamon Bark Oil, Ceylon Type, 101, 578... 

It has been assumed that the cineol and phosphoric acid enter into combination in molecular proportions, forming a solid compound of definite composition. Helbing and Passmore have described a method in which the compound is weighed, and assume that the percentage of cineol in the phosphoric compound is 61 1 per cent, based on the formula CjQHjgO. H3PO4. 

The above method is applicable directly to all oils containing above 50 per cent, of cineol in oils containing lower proportions of cineol the precipitate is not solid enough to permit convenient handling and if the cineol-content drops below 25 per cent, the separation of cineol arsenate is not quantitative. It was found that the addition of an equal volume of eucalyptol to such oils (i.e. mixing 5 c.c. of the oil with 5 c.c. of eucalyptol) successfully overcomes this difficulty it then only becomes necessary to subtract from the volume of cineol, as observed in the neck of the flask, 5 c.c., and to multiply the difference by 10, in order to obtain the percentage of cineol in the oil. 

Percentage of Cineol in Mixture. Freezing-points. Terpene Mixture. Freezing-points. Sesquiterpene Mixture.. ... 

Major components listed under a general heading for eucalyptus would be citronellal, cineole, camphene, fenchene, limonene, phellandrene and pinene. The individual species show the different proportions (amounts shown are approximate percentages) ... 

Assay Determine as directed under Solidification Point, Appendix IIB, drying a sample over anhydrous sodium sulfate. Transfer 3 g of the dried oil, accurately weighed, into a test tube, and add 2.1 g of melted o-cresol. The o-cresol must be pure and dry and have a solidification point not below 30°. Insert the thermometer, stir, and warm the tube gently until the mixture is completely melted. Continue as directed in the method. Repeat the procedure until two successive readings agree within 0.10°. Compute the percentage of cineole from the table found under Percentage of Cineole, Appendix VI. Acid Value Determine as directed under Acid Value, Appendix VI. 

Twelve patients with chronic obstructive bronchitis were given a 4-day treatment with 1,8-cineole (4 X 200 mg/day). By measuring the reduction in percentage radioactivity of an applied radioaerosol, signi cant improvements in mucociliary clearance were demonstrated at the 60 and 120 min after each administration, (Dorow, 1989). 

Hassiotis and Lazari examined the bacterial population growth during degradation of Myrtus communis L. (Myrtaceae) essential oil. It could be shown that the bacterial population was able to grow and use myrtle essential oil, whose compounds were decreasing over the time, as energy source. At the end of the study, only low percentages of 1,8-cineole and camphene could be detected (Hassiotis and Lazari, 2010). 

Of the literature published in peer-reviewed journals over the last 30 years, only a small percentage concerns the administration of essential oils or their components to humans in order to treat disease processes. These reports are listed below in alphabetical order of their activity. The exception is the section on the respiratory tract, where the many activities of the two principal components (menthol and 1,8-cineole) are discussed and related to respiratory pathologies. 

Find the percentage w/w of cineole corresponding to the freezing-point from the following Table, obtaining intermediate values by interpolation ... 

Determine the congealing-point of the sassafras oil in the apparatus used for cineole (see p. 725). Construct a graph correlating freezing-point and percentage safrole from Table 54 (Shukis and Wachs ). 

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