Cinchocaine chloride

Egfjord, M., J.A. Jansen, H. Flachs, and J.S. Schou. 1988. Combined boric acid and cinchocaine chloride poisoning in a 12-month-old infant evaluation of haemodialysis. Human Toxicol. 7 175-178. 

A 23-year-old woman developed an allergic contact dermatitis after applying an over-the-counter proprietary antipruritic jelly containing 0.1% cinchocaine chloride, and a caine mixture (5% benzocaine, 1% cinchocaine hydrochloride, 1% procaine hydrochloride) (39). She had positive patch testing to both components. 

A 71-year-old Japanese man, who was using an over-the-counter formulation, Makiron, for minor wounds, developed an itchy rash with seropapules and erosions on his right leg at the site of application (5). Makiron contains 0.1% cinchocaine hydrochloride and chlorphe-namine maleate as well as naphazoline hydrochloride and benzethonium chloride. On patch testing, he was positive to both chlorphenamine and cinchocaine. 

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