Chloro ethyl ether

Synonyms AI3-04504 BCEE Bis(P-chloroethyl) ether BRN 0605317 Caswell No. 309 Chlorex l-Chloro-2-(P chloroethoxy)ethane Chloroethyl ether 2-Chloroethyl ether (P-Chloro-ethyl) ether CCRIS 88 DCEE Dichlorodiethyl ether 2,2 -Dichlorodiethyl ether p,P -Dichlorodi-ethyl ether Dichloroether Dichloroethyl ether a,a -Dichloroethyl ether Di(p-chloroethyl) ether Di(2-chloroethyl) ether sj/n-Dichloroethyl ether 2,2 -Dichloroethyl ether Dichloroethyl oxide l,5-Dichloro-3-oxapentane EINECS 203-870-1 ENT 4504 EPA pesticide chemical code 029501 NSC 406647 l,l -Oxybis(2-chloroethane) RCRA waste number U025 UN 1916. 

G. 63. Ethylene qlycol derivatives bis(2-chloro- ethyl)ether - trace 98 ND ... 

An improved procedure has been described more recently. Note that bis(2-chloro-ethyl) ether is available from Eastman. 

GC and GC/MS are the most widely used techniques for the analysis of bis(2-chloro-ethyl)ether. Methods for analysis of this compound in wastewaters and soils and solid wastes along with other haloethers are described in EPA procedures (U.S. EPA 1992, Methods 611, 625 1986, Methods 8010 and 8270). 

Cyclopropane derivatives have been prepared using alkenes, cm-dihalides, and copper. This is a convenient and useful procedure, e.g. cis-cyclo-octene was converted into bicyclo[6,l,0]nonane (77%) and into a mixture of endo- and cxo-9-methoxy-carbonylbicyclo[6,l,0]nonanes (71 % exo. endo = 1.3 1) using di-iodomethane and methyl dibromoacetate, respectively. An improved procedure for the conversion of alkenes into cyclopropanols uses lithium 2,2,6,6-tetramethylpiperidide and 2-chloroethyl chloromethyl ether, e.g. cycloheptene was converted into the 2-chloro-ethyl ether of bicyclo[5,l,0]octan-8-ol (62% exo.endo = 1.8 1). ... 

Chloro Ethyl Ether. Ethylene Chlorohydnn - 302 150 E E — G still system tor cracking Dl (2-chloroethyl) acetal to vinyl 2-chloroethyl ethers and ethylene chlorohydnn. Samples in kettle liquid. 300 hrs. 

C. It can be obtained from its hahde-free solutions in cyclohexane and ethylether by vacuum distUlation to remove the ether. The usual preparative method is by reaction of chloro- or bromobenzene and lithium metal in ethyl ether or in a mixture of ethyl ether and cyclohexane. 

Table 2 gives physical property data for propylene chlorohydrins. 2-Chloro-l-propanol [78-89-7] HOCH2CHCICH2, is also named 2-propylene chlorohydrin, 2-chloropropyl alcohol, or 2-chloro-l-hydroxypropane. l-Chloro-2-propanol [127-00-4] CICH2CHOHCH2, also known as j -propjlene chlorohydrin, 1-chloroisopropyl alcohol, and l-chloro-2-hydroxypropane, is a colorless Hquid, miscible in water, ethanol, and ethyl ether. 

Chloro-l,2-propanediol [96-24-2] HOCH2CHOHCH2CI, a liquid with = 1.4831 (6), boils at 213°C and 101.3 kPa (1 atm) with decomposition. It can be distilled at 114—120°C at 1.87 kPa (14 mm Hg). Synonyms for this compound include 3-chloro-l,2-dihydroxypropane, glycerol monochlorohydrin, a-chlorohydrin, and 3-chloropropylene glycol. It is miscible in water, ethanol, ethyl ether, and acetone [67-64-1] (8) and is soluble in hot... 

In the first step, 2-chloro-4-aminobenzoyl chloride hydrochloride is prepared by refluxing a mixture of 25 cc of purified thionyl chloride and 10 g of 2-chloro-4-aminobenzoic acid until all of the solid has gone into solution. To the cooled solution is added 150 cc of dry ethyl ether. A brisk stream of dry hydrogen chloride is passed into the solution until the precipitation of 2-chloro-4-aminobenzoyl chloride hydrochloride is complete. The acyl halide is removed by filtration and dried in a vacuum desiccator. 

If 18 parts of piperidine are used instead of 12 parts of methylethylamine then the same procedure results in the formation of p-chloro-benzyhydril-(/3-piperidino-ethyl) ether, boiling at 178° to 180°C under 0.15 mm pressure. 

Prepares solution of sodium methylate by dissolving 3.9 g of sodium metal in 500 ml of methanol. Add 39.0 g of 7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazeplne-2-one. Evaporate the reaction mixture to a residue and dissolve the residue in 170 ml of dimethylformamide. Add 30 g of 2,2,2-trifluoroethyl Iodide and stir at room temperature for Vi hour, then heat to 60°C to 70°C for an additional 7 hours. Add 19 g of 2,2,2-trifluoroethyl iodide and resume the heating and stirring at 60°C to 70°C for an additional 16 hours. Filter off the solids and evaporate the filtrate to a residue in vacuo. Triturate the residue with water and extract with ethyl ether. Wash the ethereal extract with water, dry over anhydrous sodium sulfate and evaporate the solvent to a residue. 

Chloro-2-methyl-3-d i met hylamino-propane T rimeprazine Chloromethyl ethyl ether Terofenamate... 

Broxton and Bunnett (1979) determined the products of the reaction of 4-chloro-3-nitrobenzenediazonium ions with ethoxide ion in ethanol, which is exactly analogous to the reaction in methanol discussed earlier in this section. These authors found 12.8% 4-chloro-3-nitrophenetole, 83% 2-chloronitrobenzene, and 0.8% 2-nitrophenetole. When the reaction was carried out in C2H5OD, the first- and second-mentioned products contained 99% D and 69% D respectively. Dediazoniation in basic ethanol therefore results in a higher yield of hydro-de-diazoniation with this diazonium salt compared with the reaction in methanol. This is probably due to the slightly higher basicity of the ethoxide ion and to the more facile formation of the radical CH3-CHOH (Packer and Richardson, 1975). Broxton and McLeish (1983 c) measured the rates of (Z) — (E) interconversion for some substituted 2-chlorophenylazo ethyl ethers in ethanol. 

A gas liquid chromatographic (GLC) method was described for determining residues of Bayer 73 (2-aminoethanol salt of niclosamide) in fish muscle, aquatic invertebrates, mud, and water by analyzing for 2-chloro-4-nitroaniline, a hydrolysis product of Bayer 73 [83]. Residues were extracted with acetone-formic acid (98 + 2), and partitioned from water samples with chloroform. After sample cleanup by solvent and acid base partitioning, the concentrated extract was hydrolyzed with 2N NaOH and H202 for 10 min at 95°C. The 2-chloro-4-nitroaniline was then partitioned hexane ethyl ether (7 + 3) and determined by electron capture GLC. Average recoveries were 88% for fish, 82% for invertebrates, 82% for mud, and 98% for water at 3 or more fortification levels. 

Chloroethyl benzoate, 30,11 a-Chloroethyl ethyl ether, 36, 60 Chlorohydroquinone, 35, 27 -Chloromandelic acid, 35,14 Chloromethylation, 30, 68 2-Chloro-2-methylcyclohexanone, 37, 8... 

Carbon tetrachloride, 0322 Carbon tetrafluoride, 0349 Carbon tetraiodide, 0525 f 1-Chlorobutane, 1637 f 2-Chlorobutane, 1638 f Chlorocyclopentane, 1923 f l-Chloro-l,l-dilluoroethane, 0731 Chlorodilluoromethane, 0369 f Chloroethane, 0848 Chloroform, 0372 f Chloromethane, 0432 f l-Chloro-3-methylbutane, 1986 f 2-Chloro-2-methylbutane, 1987 f Chloromethyl ethyl ether, 1246 f Chloromethyl methyl ether, 0850 f l-Chloro-2-methylpropane, 1639 f 2-Chloro-2-methylpropane, 1640 f 1-Chloropentane, 1988 f 1-Chloropropane, 1243 f 2-Chloropropane, 1244 f l-Chloro-3,3,3-trifluoropropane, 1127 1,2-Dibromoethane, 0785 Dibromomethane, 0395... 

Bis-(2-methoxyethyl) ether, 2549 f 1,3-Butadiene, 1480 f 1,3-Butadiyne, 1385 f 2-Butanol, 1695 f Buten-3-yne, 1423 f Butyl ethyl ether, 2540 f Butyl vinyl ether, 2484 f 2-Chloro-1,3-butadiene, 1451 f Chloroethylene, 0730 f 2-Chloroethyl vinyl ether, 1557... 

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