Cortex Chinae

Test mixtures Cinchona alkaloids test mixture for Cinchonae (Chinae) cortex (DAB 10)... 

Chloroform-dielhylainine (90 10) Chinae cortex Cinchona alkaloids... 

Chinae cortex Ciuchonae cortex Red Cinchona bark Cinchona pubescens VAHL (syn. C. sucdrubra PAVON) DAB 10, OAB, Helv. VII, MD DAC 86 (tinct.)... 

Fig. I2A In the R, range 0.05-0.25 both Cinchona (Chinae Cortex) extracts show six light blue fluorescent alkaloid zones in UV-365 nm. They can be differentiated on the basis of their quinine (Tl) content. In C. calisaya cortex (1) quinine counts as a major alkaloid. C.

China Aster ageratoides L. Quercetin, kaempferol.33 Antitussive, antiasthmatic, stimulate adrenal cortex. 

The bark of Eucowmia ulmoides has been used as a tonic and antihypertensive medicine in Japan and China, which is available on the market as the Chinese Crude Drug "Cortex Eucommia . 

J.L. Liu, Y.B. Tan, Z.L. Zuang, X.Y. Zhu and B.Z. Chen, Morphologic study of development of cerebral cortex of therapeutically aborted fetuses in endemic goiter region, Gui-Zhou Province, China, ... 

Hsu, C.-S. Studies on the Hypotensive Effect of Some Extracts of Cortex Mori Radicis Produced in China and Japan. Kansai Ika Daigaku Zasshi (The J. of Kansai Medical Univ.) 16,110 (1964). 

The neurotoxicity of acrylamide in humans is well known from occupational and accidental exposures [51], For instance, Calleman et al. [52] reported peripheral neuropathy symptoms to highly exposed workers in China. It is characterized by skeletal muscle weakness, numbness of hands and feet, and ataxia. Acrylamide has been shown to be toxic to both the central and the peripheral nervous system [53], although the nerve terminal is now considered to be the primary site of acrylamide action [54,55]. Acrylamide induces nerve terminal degeneration and has effects on the cerebral cortex, thalamus, and hippocampus [56]. In double-blind studies of factory workers, no neurotoxicity was found in workers exposed to less than 3.0 mg/kg/ day as determined by biomonitoring [55]. A very recent study demonstrates structural and ultra structural evidence of neurotoxic effects of fried potato chips on rat postnatal development. 

Cortex Fraxini / Fraxinus chinensis Province Hunan, China... 

Cortex Dictamnus dasycarpus (bai xian pi) and Radix Sophora flavescens (ku shen), is commonly used to treat hematochezia, anal bulge, and constipation caused by hemorrhoids. The State Food and Drug Administration of China (SFDA) has received several reports of adverse reactions to Zhi xue capsule in recent years [7, 8 ]. Up to September 2008, 35 cases of adverse reactions associated with Zhi xue capsule had been reported, of which 21 were associated with abnormal liver function, cholestatic hepatitis, and drug-induced liver damage. After withdrawal and symptomatic treatment, there was full recovery in eight cases, and the rest improved markedly. 

Common/vernacular names Red bark, red Peruvian bark, cinchona rubra (C. pubescens), yellow bark, calisaya bark, ledger bark, brown bark, cinchona flava (C. calisaya and C. ledgeriana), Jesuit s bark, Peruvian bark, China bark, cortex chinae, and fever tree. 

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