Mace, chemical

Synonyms AI3-52322 BRN 0507950 CAP CAP Caswell No. 179C CCRIS 2370 Chemical mace 1-Chloroacetophenone 2-Chloroacetophenone Q-Chloroacetophenone Chloromethyl phenyl ketone 2-Chloro-l-phenylethanone CN EINECS 208-531-1 EPA pesticide chemical code 018001 Mace NC1-C55107 NSC 41666 Phenacyl chloride Phenyl chloromethyl ketone Tear gas UN 1697. 

CF 2, see 1,1,1-Trichloroethane CFC 11, see Trichlorofluoromethane CFC 21, see Dichlorofluoromethane CFC 112, see 1,2-Difluorotetrachloroethane CFC 112a, see 1,1-Difluorotetrachloroethane CFC 113, see 1,1,2-Trichlorotrifluoroethane Chelen, see Chloroethane Chemform, see Methoxychlor Chemathion, see Malathion Chemical 109, see ANTU Chemical mace, see a-Chloroacetophenone Chemox PE, see 2,4-Dinitrophenol Chempenta, see Pentachlorophenol Chemphene, see Toxaphene Chemrat, see Pindone Chemsect DNOC, see 4,6-Dinitro-ocresol Chemtol, see Pentachlorophenol Chevron acetone, see Acetone Chimec NR, see 2-Bntoxyethanol Chinone, see / Qninone Chinnfnr, see Carbofuran Chipco thiram 75, see Thiram Chipco turf herbicide "D", see 2,4-D Chladone 11, see Trichlorofluoromethane Chlon, see Pentachlorophenol Chlorallylene, see Allyl chloride Chloran, see Lindane 4-Chloraniline, see 4-Chloroaniline p-Chloraniline, see 4-Chloroaniline Chlorbenzene, see Chlorobenzene Chlorbenzol, see Chlorobenzene p-Chlor-ro-cresol, see p-Chloro-ro-cresol Chlordantoin, see Amyl acetate Chlordan, see Chlordane... 

Synonyms 2-Chloro-l-phenylethanone phenacyl chloride phenyl chloromethyl ketone tear gas chemical Mace... 

Sporadic cases of dermatitis due to primary irritation by a-chloroacetophenone have been reported. Allergic contact dermatitis to this substance in chemical Mace has been documented by patch test evaluation, and it is said to be a potent skin sensitizer. ... 

Penneys NS, Israel RM, Indgin SM Contact dermatitis due to 1-chloroacetophenone and chemical Mace. N Engl J Med 281 413M15, 1969... 

The chlorinated acetones are strong lachrymalors. Tear gas contains chloroacelophenonc. which is also a component of the nonlethal disabling spray chemical Mace. 

CN is a crystalline solid with a strong, pungent odor (see Figure 12.3). It is dispersed as a smoke, powder, or liquid formulation from grenades or other devices. It is perhaps better known under the trade name Chemical Mace and was once used widely for self-protection. It was also the standard tear gas used by the military (Figure 12.4) and police personnel. It has been replaced in favor of the less toxic CS for riot control and capsaicin pepper spray for self-defense. 

Mace [Mace]. ( Chemical Mace ). TM for a riot-control gas dispersed as an aerosol. 

King, K., Tunget, C.L, Turche, B., Monguerra, A., and Clark, R.E., Severe contact dermatitis from chemical mace containing 1-chloroacetophenone, Cutan. Ocul. Toxicol., 14, 57-62, 1995. 

MacLeod, I.F., Chemical mace ocular effects in rabbits and monkeys, J. Forensic Sci., 14, 34-37, 1969. 

Kling RP (1969). Chemical mace - a controversy. Eye Ear Nose Throat Monthly, 48, 13. 

Beilstein Handbook Reference) Acetophenone, 2-chloro- AI3-52322 BRN 0507950 Caswell No. 179C CCRIS 2370 Chemical mace Chloroacetophenone a-Chloroacetophenone 1-Chloroacetophenone 2-Chloro-1-phenylethanone 2-Chloroacetophenone Chloromethyl phenyl ketone CN CN (lacrimator) EINECS 208-531-1 EPA Pesticide Chemical Code 018001 Ethanone, 2-chloro-1-phenyl- HSDB 972 Mace (lacrimator) NCI-C55107 NSC 41666 ra-Chloroacetophenone Phenacyl chloride Phenacylchloride Phenylchloromethylketone UN1697. Pharmaceubcal intermediate. A lachrymator, is the primary component of Mace, a riot-control gas. Plates, mp = 56.5° bp = 247° d n 1,324 insoluble in H2O soluble in MezCO, petroleum ether, very soluble in EtOH, EtzO, C6H6, CS2 LDso (rat ori) = 127 mg/kg. Janssen Chimica Lancaster Synthesis Co. Penta Mfg. 

This is parsimony which would not be in the sense of a synthetic chemist synthesizing a new drug molecule It is not directed towards specificity but serves rather the opposite to obtain a broad-band chemical mace as efficacious as possible against as many targets as possible. This section has shown the enormous versatility of STL structure and the major determinants of their structural diversity. In this light on the outstanding success of STLs as secondary natural products in evolution the next section will focus in more detail on reactivity as the basis of this success, and on particular structure-activity relationships associated therewith. 

OTHER COMMENTS used in the manufacture of tear gas and chemical mace used as a pharmaceutical intermediate former use as an alcohol denaturant. 

Synonyms cas 532-27-4 mace chemical mace phenacyclchloride phenyl chloromethyl ketone... 

By converting CN or CS agent into talc-size dustlike ( microniz-ed ) particles and expelling it from a nonfragmenting grenade by the action of a piston, an effective dust cloud of highly irritating material that adheres to clothes and moist skin areas can be created. A similar principle is involved in an item called by the tradename Chemical Mace in which the offensive material is dispersed in a liquid solu-tion. "... 

Chemical mace. See Chloroacetophenone Chemld CDA-200. See Cocamide DEA Chemld ODA-100. See Oleamide DEA Chemidex B. See Behenamidopropyl dimethylamine... 

---