Chemical Laboratory Information Profiles

Chemical Laboratory Information Profiles (CLIPs) are very useful synopses of the hazards of laboratory chemicals. 

Laboratory Chemical Safety Summaries (LCSSs) in Prudent Practices in the Laboratory Handling and Disposal of Chemicals (Updated Edition), Supplementary Material 10 http //www.ncbi.nlm.nih.gov/books/NBK55861/ Chemical Laboratory Information Profiles (CLlPs) http //www.acs.org/content/acs/en/about/govemance/ committees/chemicalsafety/safetypractices/clips-list.html... 

Disposal of hazardous waste is dangerous and expensive, even when the contents of the waste are identified. Fortunately, most chemical waste produced in a laboratory or work area is identifiable. When the contents of a reagent bottle, reaction flask, or gas cylinder are not identified, the process of disposal is more dangerous, expensive, and difficult. Without mitigating information, all unknown materials must be treated as if they were potentially lethal and hazardous. In all cases, chemical unknowns cannot be disposed of until a general profile of the unknown has been generated. Even then, the disposal cost is a premium. Additionally, there is a constant threat of personal injury or death to individuals who handle these potentially dangerous materials. No price tag can be attached to an avoidable personal injury. 

Risk Assessment Information System (from the Oak Ridge National Laboratory and the University of Tennessee) - includes toxicity profiles on chemicals - http //risk.lsd.ornl.gov International Toxicity Estimates for Risk (ITER) (from Toxicology Excellence for Risk Assessment (TERA)) - provides tabular comparisons of risk... 

The writer wishes to thank Mr. A. Holbrook of Imperial Chemical Industries Ltd., and Dr. B, T. Kho of Ayerst Laboratories Inc., for their careful reading of the manuscript and helpful suggestions for improvements, as well as Dr. J. M. Pryce of Imperial Chemical Industries Ltd., who provided the mass spectral and nuclear magnetic resonance information for this profile. 

It is also necessary for the user to take into account that fine chemicals for laboratory use are usually produced by batch processes rather than by continuous methods of manufacture. Therefore, because specifications set minimum standards of purity, the analysis of one or two batches of a given reagent from a supplier will not give reliable general information concerning the impurity profile of that product. 

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