Cellular grades

This method was eminently suitable for the determination of volatile expanding agents present in expanded cellular grades of polystyrene. Normal and isopentane are commonly used for this purpose. The method quoted next enables these and wide range of other volatiles to be determined in polystyrene with a reasonable degree of accuracy. 

Over 90% of colon cancers are adenocarcinomas and are assigned a grade of I to III based on how similar they are to normal colon cells. Grade I tumors most closely resemble normal cellular structure, whereas, grade III tumors frequently have lost the characteristics of mature normal cells. Grade III tumors are associated with a worse prognosis than grade I tumors.8... 

Nodular sclerosis Hodgkin s lymphoma (grades 1 and 2) Lymphocyte-rich classical Hodgkin s lymphoma Mixed cellularity Hodgkin s lymphoma Lymphocyte depletion Hodgkin s lymphoma... 

Celis A et al. Short-term culturing of low-grade superficial bladder transitional cell carcinomas leads to changes in the expression levels of several proteins involved in key cellular activities. Electrophoresis 1999 20 355-361. 

Ligand-bound corticosteroid receptors have been shown to interact to form heterodimers with other transcription factors, such as the jun protein. Such interactions are responsible for transactivation of the ds-regulatory sites known as AP-1 sites and for the glucocorticoid-mediated suppression of transcription, such as that seen in the pro-opiomelanocortin gene. A number of such specific protein interactions have been reported these interactions and their locations relative to other transcription factors transform a ubiquitous steroid hormone signal into a tissue-specific, graded cellular response. 

A murine model of food-induced atopic dermatitis confirmed the important role of specific T cells in eczema here, C3H/HeJ mice were orally sensitized to cow s milk or peanut and thereafter exposed to the allergen. An eczematous eruption developed in approximately one third of mice after low-grade exposure to milk or peanut proteins. Histological examination of lesional skin revealed spongiosis and a cellular infiltrate mainly consisting of CD4-I- lymphocytes. 

The grade of vulvar intraepithelial neoplasia (VIN) can be scored by subclassifying it on the basis of the extent of cellular changes into three types (Van Beurden et al., 1999) ... 

A 4.5 ml aliquot of each concentration of the test substance is mixed with a 0.5 ml aliquot of test medium containing any requested organic soil load in lieu of virus and treated as previously described. The cytotoxicity of the cell cultures was scored at the same time as virus-test substance and virus control cultures. Cytotoxicity was graded on the basis of cell viability as determined microscopically. Cellular alterations due to toxicity were graded and reported as toxic (T) if greater than or equal to 50% of the monolayer is affected. 

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