Cartilage development

Fluoroquinolones Tendonitis, Achilles tendon rupture, contraindicated in patients less than 18 years old because of effects on cartilage development... 

Hayes AJ, Dowthwaite GP, Webster SV and Archer CW (2003) The distribution of Notch receptors and their ligands during articular cartilage development. J. Anat. 202 495-502. 

Shimizu T, Nakano K, Tsujigiwa H, Nagatsuka H, Watanabe T, Okafuji N, Kurihara S, Hasegawa H, Nagai N and Kawakami T (2007) Notch signaling in mandibular condylar cartilage development. Eur. J. Med. Res. 12 515-519. 

Kawakami T and Shimizu T (2009) Role of Notch signaling in mouse mandibular condylat cartilage development. Acta. Anat. Nipponica 84(S) 69. 

X [ 1(X)]3 Cartilage developing into bone May associate with a membrane gene contains only one intron... 

CDMP. cartilage-derived morphogenetic protein Cartilage development... 

Contraindicated in pregnancy and children, based on animal studies showing effects on collagen metabolism and cartilage development tendonitis (and tendon rupture) has occurred in adults. 

Proteoglycan PG-M Domestic fowl Cassette 2 forms differing by 100 kDa chondroitin sulphate proteoglycan involved in cartilage development Shinomura el al. (1993)... 

In Muller s work [51], non-woven cellulose II fabrics were used as scaffolds for in vitro cartilage tissue engineering. The scaffolds were activated in a saturated Ca[OH]2 solution and subsequently coated with a calcium phosphate layer precipitated from a supersaturated physiological solution. Chondrocyte cell response and cartilage development were investigated. The cell adherence was significantly improved compared to untreated cellulose fabrics, and the proliferation and vitality of the adhered chondrocytes were excellent, indicating the biocompatibility of these materials. 

Mooney, M.P., Siegel, M.L, Kimes, K.R., Todhunter, J.S. Smith, T.D. 1994. Anterior paraseptal cartilage development in normal and cleft lip and palate human fetal specimens. Cleft Palate-Craniofac. J., 31, 239-245. 

Caplan AI (1981) The molecular control of muscle and cartilage development. Liss, New York, pp 37-68... 

Caplan AI, Koutroupas S (1973) The control of muscle and cartilage development in the chick limb The role of differential vascularization. J Embryol Exp Morphol 29 571-583... 

Caplan, A.I., The molecular control of muscle and cartilage development, in 39th Annual Symposium of the Society for Developmental Biology, Subtelney, S. and Abbott, U. (Eds.), Alan R. Liss, Inc., New York, pp. 37 8,1981. 

The static hydrostatic pressure was studied at loads ranging from 1 to 10 MPa and loading scheme ranging from 1 h/day to 20 h on monolayer and 3-D scaffolds (Hall et al. 1991 Smith et al. 1996 Takahashi et al. 1997 Jortikka et al. 2000 Mizuno et al. 2002 Toyoda et al. 2003 Elder and Athanasiou 2008). The static hydrostatic pressure also shows positive results in term of aggregan and coUagen II expression, sulfated GAG and collagen production. Both the uniaxial compression and the application of hydrostatic pressure have direct affect on cell behavior and enhance cartilage development when applied at the appropriate condition. 

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