Protein morphogenetic

Bone morphogenetic proteins (BMPs) A family (eight or more) of secreted proteins with a variety of actions on bone many induce ectopic bone growth. 

Figure 5.19 Simplified genetic map of T4. Late genes with morphogenetic functions (coat proteins and assembly), and genes with functions in DNA replication are identified. Note that although the genetic map is represented as a circle, the DNA itself is actually linear.

Bio-nanocomposites based on calcium phosphates can perform other innovative fundions such as acting as a reservoir for the controlled release of bioadive compounds once the material is implanted in the bone defect. For instance, the incorporation of a morphogenetic protein that promotes bone regeneration in an HAP-alginate-collagen system [110] or a vitamin in a Ca-deficient HAP-chitosan nanocomposite [111] are recent examples of this kind of application. 

In purple bacteria investigated thus far, the development of the photosynthetic apparatus which is controlled by the oxygen partial pressure is not influenced by light. However, the prevalent light intensity modifies the morphogenetic process of formation of intracytoplasmic membranes. Light intensity also controls the total bacteriochlorophyll concentration per cell and per membrane protein, as well as regulating... 

Hu J, Sebald W (2011) N-terminal specificity of PEGylation of human bone morphogenetic protein-2 at acidic pH. Int J Pharm 413 140-146... 

Reynolds, A.M., Xia, W., Holmes, M.D., Hodge, S.J., Danilov, S., Curiel, D.T., Morrell, N.W., and Reynolds, P.N. (2007) Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension. Am. J. Physiol. Lung Cell Mol. Physiol. 292, L1182-L1192. 

Bone morphogenetic proteins stimulate astrogenesis 508 Neural crest stem cells give rise to neuronal or glial derivatives in the peripheral nervous system 509... 

Mehler, M., Mabie, P., Zhu, G., Gokhan, S. and Kessler, J. Developmental changes in progenitor cell responsiveness to bone morphogenetic proteins differentially modulate progressive CNS lineages. Dev. Neurosci 22 74-85, 2000. 

Gross, R. E., Mehler, M. F., Mabie, P. C., Santschi, L., Ngo, P. and Kessler, J. A. Promotion of astroglial lineage commitment from mammalian subventricular zone progenitor cells by bone morphogenetic proteins. Neuron 17 1-20,1996. 

Schneider, C., Wicht, H., Enderich, J., Wegner, M. and Rohrer. H. Bone morphogenetic proteins are required in vivo for the generation of sympathetic neurons. Neuron. 24 861-870,1999. 

Canalis E, Economides AN, Gazzerro E (2003) Bone morphogenetic proteins, their antagonist, and the skeleton. Endocr Rev 24 218-235... 

Rickard DJ, Hofbauer LC, Bonde SK, Gori F, Spelsberg TC, Riggs BL (1998) Bone morphogenetic protein-6 production in human osteoblastic cell lines. Selective regulation by estrogen. J Clin Invest 101 413-422... 

Hofbauer LC, Dunstan CR, Spelsberg TC, Riggs BL, Khosla S (1998) Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines. BioChem Biophys Res Commun 250 776-781... 

CUB Domain first found in Clr, Cls, uEGF, and bone morphogenetic protein E(M) 0(0) 57(95) 1SFP... 

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