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Carcinogenicity and Mutagenicity in Salmonella

While a complete rendering of the American study has not yet been published, two summary reports, which do not list the chemicals [Pg.380]

Finding Chemical Dose (Mg/plate) TA strains S-9 inducer Source [Pg.381]

Negative Aldrin 100 1535,1537, 1538, 100, 98 Aroclor T. H. Connor (unpublished data), Simmon et [Pg.381]

More mutagenic when assayed in a desiccator or in suspension than when incorporated into the agar. [Pg.381]

Nakamura S, Oda Y, Shimada T, et al. 1987. SOS-inducing activity of chemical carcinogens and mutagens in Salmonella typhimurium TA1535/pSK1002 examination with 151 chemicals. Mutat Res 192 239-246. [Pg.157]

Dunkel VC, Zeiger E, Brusick D, et al. 1985. Reproducibility of microbial mutagenicity assays. II. Testing of carcinogen and noncarcinogens in Salmonella typhimurium and Escherichia coli. Environ Mutagen (SuppI 5) 7 1-248. [Pg.117]

McCann, J., Choi, E., Yamasakim, E. and Ames, B.N. (1975a) Detection of carcinogens as mutagens in Salmonella/microsome test Assay of 300 chemicals. Proc. Natl. Acad. Sci. USA, 72(12), 5135-5139. [Pg.254]

Matthew EJ, Spalding JW, Tennant RW (1993) Transformation of BALB/c-3T3 cells via transformation responses of 168 chemicals compared with mutagenicity in salmonella and carcinogenicity in rodent bioassays. Environ Health Perspect 101 347 182... [Pg.151]

Among the chemicals which have been shown to be mutagens in Salmonella (as well as other short-term tests) that have recently been shown to be carcinogens are 1,2-dichloroethane (10 x 109 Ibs/year, U.S.), tris-dibromopropyl phosphate (the flame retardant used in children s polyester sleepwear), sulfallate (a pesticide), o-phenylene-diamine, 2,4-diaminoanisole (hair dye ingredient), 2-nitro-p-phenylenediamine (hair dye ingredient), and 4-amino-2-nitro-phenol (hair dye ingredient). [Pg.6]

The carcinogenicity of 1,2,3-trichloro-propane is consistent with positive genotoxic findings that have included mutagenicity in Salmonella typhimurium and induction of sister chromatid exchanges in cultured hamster cells. It forms DNA adducts in vivo in mice and rats. ... [Pg.703]

See other pages where Carcinogenicity and Mutagenicity in Salmonella is mentioned: [Pg.314]    [Pg.379]    [Pg.380]    [Pg.385]    [Pg.421]    [Pg.314]    [Pg.379]    [Pg.380]    [Pg.385]    [Pg.421]    [Pg.385]    [Pg.433]    [Pg.35]    [Pg.100]    [Pg.247]    [Pg.820]    [Pg.290]    [Pg.4]    [Pg.9]    [Pg.11]    [Pg.11]    [Pg.538]    [Pg.820]    [Pg.338]    [Pg.436]   


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And carcinogenicity

CARCINOGENIC MUTAGENIC

Carcinogenicity and mutagenicity

Carcinogenicity mutagenicity

Carcinogens/mutagens

Salmonella

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