Carcinogenesis promotors

The weight of evidence from in vivo and in vitro genetic toxicology tests, in vivo liver function studies, and the two-stage tumor promotion assay is adequate to conclude that chlordecone is a promotor rather than an initiator of carcinogenesis. While the evaluation of mirex in an in vivo tumor promoter... 

Wynder E, Hoffmann D. 1961. A study of tobacco carcinogenesis. VIII. The role of acidic fractions as promotors. Cancer 14 1306-1315. 

Dietary Fat, Prolactin, and Breast Cancer. Prolactin may also interact with diet to influence breast cancer. Although the role of prolactin in human breast cancer etiology is relatively obscure, its role as a promotor in rodent mammary carcinogenesis has been well established (55,56). 

Tsujii M, Kawano S, Tsuji S, et al. 1992a. Ammonia a possible promotor in Helicobacter pylori-related gastric carcinogenesis. Cancer Lett 65(1) 15-18. 

It is now established that some agents with promoting activity will Increase neoplasia in the absence of initiation (85,87). Promotors that enhance liver carcinogenesis are of particular Interest because they include a number of pharmaceuticals, food additives, and pesticides (88-90). 

Bile salts as tumor promotors, "Carcinogenesis, Vol 2. Mechanisms of Tumor Promotion and Co-carcinogenesis," T.J. Slaga, S. Sivak, and R. K. Boutwell, eds.. Raven Press, New York (1978). 

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