Carbohydrates glycos

From the carbohydrate analyses of peak II, it was determined that 780 pg of polysaccharide (i.e., polymers of neutral monosaccharides with polymer mol. wt. of 1,000-5,000) were reversibly complexed with the estimated 19.5 pg of glycopeptide contained in this peak. Hence, the calculated carbohydrate glyco-peptide weight ratio is approximately 40 1. 

Compounds with a phosphonate group linked by a P-C bond to a carbohydrate residue may be named as glycos-n-ylphosphonates (cf. 2-Carb-31.2) or as C-sub-stituted carbohydrates (cf. amino sugars, 2-Carb-14). 

Faijes, M. and Planas, A. (2007) In vitro synthesis of artificial polysaccharides by glycosidases and glyco-synthases. Carbohydrate Research, 342, 1581-1594. 

K. Aoi, K. Tsutsumiuchi, A. Yamamoto, and M. Okada, Globular carbohydrate macromolecule sugar balls 3. Radial-growth polymerization of sugar-substituted x-amino acid N-carboxyanhydrides (glyco-NCAs) with a dendritic initiator, Tetrahedron, 53 (1997) 15415-15427. 

Glycosylated porphyrins and miscellaneous products. A few other examples of functional glyco-compounds were prepared, persuing the idea that attaching a carbohydrate moiety can provide increased polarity and water solubility to another molecular construct. Many types of compounds have been prepared in this regard (Fig. 7). For example, polymerisable... 

Analytical tools have been developed in order to identify carbohydrate structures as well as carbohydrate-binding proteins and to understand their underlying structure-function relationships of protein-carbohydrate and carbohydrate-carbohydrate interactions lectin arrays [16], glycan microarrays [17, 18], glyco-nanoparticles [19], frontal affinity chromatography [20] and carbohydrate tools for metabolic labeling [21]. 

In summary, for aU of the above-mentioned applications, the synthesis of carbohydrates and derivatives thereof is necessary to foster the field of glyco-engineering. Many procedures have been established to produce synthetic (neo)glycoconjugates by chemical or enzymatic methods and these are summarized in excellent reviews [12, 27, 28]. 

Enzymes. See also, Amylases, Galactosi-dases, /3-Glucuronidase, Glyco-enzymes, a-D-Mannosidase. acting on pectic substances, 5, 79-102 degradation by, of starch and glycogen, 3, 251-310 17, 407-430 of glycoprotein structure, 27, 301-341 specificity of, in the domain of carbohydrates, 5, 49-78... 

Polyfructosans. See Fructans. Polyglycosiduronic acids. See Glyco-siduronic acids, poly-. Polysaccharides. See also, Carbohydrates,... 

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