Capacity factor physicochemical properties

Once the type of packaging material is decided based on such factors as size, shape, capacity, and physicochemical properties, all these data, including quality control tests, should be included in the specification of the products in order to assure the therapeutic effectiveness during its shelf life. 

Contaminants may reach the subsurface in a gaseous phase, dissolved in water, as an immiscible hquid, or as suspended particles. Contaminant partitioning in the subsurface is controlled by the physicochemical properties and the porosity of the earth materials, the composition of the subsurface water, as well as the properties of the contaminants themselves. While the physicochemical and mineralogical characteristics of the subsurface sohd phase define the retention capacity of contaminants, the porosity and aggregation stams determine the potential volume of liquid and air that are accessible for contaminant redistribution among the subsurface phases. Enviromnental factors, such as temperature and water content in the subsurface prior to contamination, also affect the pollution pattern. 

The solubilizing capacity for a given surfactant system is a complex function of the physicochemical properties of the two components which, in turn, influence the location or sites where the drug is bound to the micelle. The molar volume of the solubilizate together with its lipophilicity are important factors, the former reducing and the latter increasing solubilization. ... 

Problems of selection of granular activated carbons in connection with their application for water treatment have been discussed. Analysis of some factors influencing adsorption has been carried out and solution of technolc ic systems has been invented. Physicochemical properties of granular activated carbons of different European firms have been tested. Adsorption capacities of carbons for some model substances of different groups of pollutants have been established. Adsorption in static and dynamic conditions has been compared and correlated. 

Solid phase extraction is used primarily to prepare liquid samples and extracts of semi-volatile or non-volatile analytes, but may also be used for solids pre-extracted into solvents. The choice of sorbent is the key factor in SPE, because this can control parameters such as selectivity, affinity, and capacity. This choice depends primarily on the analytes and their physicochemical properties, which should define the interactions with the chosen sorbent. However, results also depend on the kind of sample matrix and interactions with both the sorbent and the analyte. SPE sorbents range from chemically bonded silicas, such as with the C8 and C18 organic groups, to graphitized carbon. 

A number of factors such as age, sex, fasting, disease, genetics, and pregnancy influence the metabolism of drugs. For example, drug metabolism capacity is lower in infants because metabolic enzyme systems are only partially developed at birth. Other factors such as physicochemical properties and physiologic variables affect drug metabolism. For example, lipid-soluble compounds are primarily... 

The requirement of good biocompatibility and partitioning behavior of substrate and product are restrictive criteria for the selection of a suitable solvent. Many attempts have been made to correlate the toxicity of different solvents to their physicochemical properties. Laane et al. first addressed this issue in a comprehensive fashion and pointed out that the logarithm of the partition coefficient, logP, as an indicator of solvent hydrophobicity, correlates best with enzyme activity [14]. The product recovery capacity and selectivity are quantified by the partition coefficient and the separation factor whose accurate values can only be obtained experimentally, but preliminary screening can be done with established databases [15]. 

The importance of plasma proteins needs no emphasis. They are polyvalent electrolytes responsible for many physicochemical and biological properties of blood, such as its buffering capacity [37]. The plasma protein fraction maintains red cells in suspension and lubricates their passage through capillaries. The viscosity of the plasma proteins is responsible for the resistance to blood flow, and the osmotic effect is an important factor in regulating water distribution between blood and interstitial tissue. Antibodies and carriers of normally poorly soluble compounds (lipids, lipid-soluble vitamins, cholesterol, metal, etc., and some nutrients) are plasma proteins. 

Some physical properties (e.g., water-binding capacity, gelatinization temperature, swelling power) of starches from pearl millets have been studied. Some starches were shown to retrograde more readily than others. Only small variations were found in the amylose content of the starches, suggesting that other physicochemical factors may be more important in determining the properties of the starches. 

---