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Cancer, monoclonal antibodies against

Bevacizumab (Avastin) Monoclonal antibody against ligand VEGFR Cancer Clinic... [Pg.1011]

Cetuzimab (Erbitux) Monoclonal antibody against EGF receptor Refractory colorectal cancer in combination with irinotecan Randomized Phase II trial... [Pg.447]

Slamon, D.J. et al.. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2, N. Engl.. Med., 344, 783-792, 2001. [Pg.456]

Cetuximab (Erbitux) is a monoclonal antibody against the epidermal growth factor receptor, EGFR. It is approved for treatment of colorectal cancer. The development of Erbitux was much in the news in 2004 as a result of insider stock trading at ImClone in the face of an initial turndown by the FDA. The former head of ImClone, Sam Waksal, is spending a term of 7 years in jail for his role in the affair. Martha Stewart completed a jail term of several months in the same case. Erbitux was subsequently approved by the FDA on the basis of additional clinical information. [Pg.349]

Starling N, Cunningham D. Monoclonal antibodies against vascular endothehal growth factor and epidermal growth factor receptor in advanced colorectal cancers present and future directions. Curr Opin Oncol 2004 16 385-90. [Pg.83]

Cetuximab is a chimeric monoclonal antibody, against epidermal growth factor receptor (EGFR). It is given by intravenous injection with weekly intervals for the treatment of metastatic colorectal cancer and head and neck cancer. It is given in combination with the chemotherapeutic agent irinotecan. The... [Pg.461]

Slamon, D. J., Leyland-Jones, B., Shak, S., Fuchs, H., Paton, V., Bajamonde, A., Fleming, T., Eirmann, W., Wolter, J., Pegram, M., Baselga, J., and Norton, L. 2001. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic cancer that overexpresses HER2. N. Engl. J. Med. 344 783-792. [Pg.342]

Onuma, M. Odawara, T. Watarai, S. Aida, Y. Ochiai, K. Syuto, B. Matsumoto, K. Yashuda, T. Eujimoto, Y. Izawa, H. Kawakami, Y. Antitumor effect of adriamycin entrapped in liposomes conjugated with monoclonal antibody against tumor-associated antigen of bovine leukemia cells. Jpn. J. Cancer Res. 1986, 77, 1161-1167. [Pg.1148]

Pimm MV, Robins RA, Embleton MJ, et al. A bispecific monoclonal antibody against methotrexate and a human tumor associated antigen augments cytotoxicity of methotrexate-carrier conjugate. Br J Cancer 1990 61 508-513. [Pg.393]

Ding L, Samuel J, MacLean GD, et al. Effective drug-antibody targeting using a novel monoclonal antibody against the proliferative compartment of mammalian squamous carcinomas. Cancer Immunol Immunother 1990 32 105-109. [Pg.393]

Rowlinson, G., Balkwill, F., Snook, D., Hooker, G., andEpenetos, A. A. (1986) Enhancement by gamma-interferon of in vivo tumour radiolocahzation by a monoclonal antibody against HLA-DR antigen. Cancer Res. 46, 6413-6417. [Pg.111]

Cordell J, Richardson TC, Pulford KAF, et al. Production of monoclonal antibodies against human epithelial membrane antigen for use in diagnostic immunocytochemistry. Br J Cancer. 1985 52 347-354. [Pg.126]

Hilkens J, Buijs F, Hilgers J, et al. Monoclonal antibodies against human milk-fat globule membtanes detecting differentiation antigens of the mammary gland and its tumors. Int J Cancer. 1984 34 197-206. [Pg.249]

See other pages where Cancer, monoclonal antibodies against is mentioned: [Pg.446]    [Pg.55]    [Pg.54]    [Pg.404]    [Pg.359]    [Pg.441]    [Pg.461]    [Pg.245]    [Pg.245]    [Pg.297]    [Pg.318]    [Pg.29]    [Pg.67]    [Pg.171]    [Pg.814]    [Pg.45]    [Pg.47]    [Pg.286]    [Pg.255]    [Pg.3481]    [Pg.426]    [Pg.84]    [Pg.2453]    [Pg.29]    [Pg.219]    [Pg.414]    [Pg.722]   
See also in sourсe #XX -- [ Pg.510 ]



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Cancer monoclonal antibodies

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