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Cancer growth measurement

Formation of regional lymph node metastasis can be an important step in dissemination of cancer cells. In colorectal cancer, lymph node metastasis frequently occurs in patients (7, 8) and is an important factor in staging the disease. In particular, the metastatic lymph node ratio (LNR number of metastatic lymph nodes/number of examined lymph nodes) is predictive of overall survival (OS) and disease-free survival (DFS) in colorectal cancer patients (9, 10). Hence, an animal model of colorectal cancer with measurable lymphatic metastasis that allows for rapid evaluation of the effects of candidate treatment regimens on primary tumor growth and lymph node metastasis would be of great value. [Pg.236]

EGER epidermal growth factor receptor (cancer cell marker that is a target for anti-neoplastic therapy) ELISA enzyme-linked immunosorbent assay (measurement method)... [Pg.446]

The effect of many drugs used to treat cancer also reflects a cumulative action—eg, the extent of binding of a drug to DNA is proportional to drug concentration and is usually irreversible. The effect on tumor growth is therefore a consequence of cumulative exposure to the drug. Measures of cumulative exposure, such as AUC, provide a means to individualize treatment. [Pg.69]

Callagy, G., Dimitriads, E., Harmey, J., Bouchier-Hayes, D., Leader, M., and Kay, E. 2000. Immunohistochemical measurement of tumor vascular endothelial growth factor in breast cancer. Appl. Immunohistochem. Mol. Morphol. 8 104-109. [Pg.310]

See other pages where Cancer growth measurement is mentioned: [Pg.46]    [Pg.195]    [Pg.431]    [Pg.196]    [Pg.730]    [Pg.247]    [Pg.160]    [Pg.1493]    [Pg.234]    [Pg.1314]    [Pg.1335]    [Pg.173]    [Pg.223]    [Pg.440]    [Pg.199]    [Pg.408]    [Pg.193]    [Pg.149]    [Pg.927]    [Pg.809]    [Pg.115]    [Pg.377]    [Pg.294]    [Pg.330]    [Pg.331]    [Pg.550]    [Pg.199]    [Pg.186]    [Pg.477]    [Pg.60]    [Pg.112]    [Pg.359]    [Pg.369]    [Pg.13]    [Pg.234]    [Pg.809]    [Pg.293]    [Pg.1162]    [Pg.1162]    [Pg.3]    [Pg.119]    [Pg.928]    [Pg.368]    [Pg.930]    [Pg.378]    [Pg.179]   
See also in sourсe #XX -- [ Pg.247 ]



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Cancer growth

Growth measurements

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