Cancer/carcinoma early gastric

Early gastric cancer is defined as gastric carcinoma that is limited to the mucosa and submucosa with or without associated lymphadenopathy (Gore et al. 1997). At double-contrast barium meal early gastric cancer appears as an elevated poly-... 

In a study investigating the prediction of response to preoperative chemotherapy in gastric carcinoma, Ott et al. [85] included 44 patients with locally advanced gastric cancer. Using the same criterion for differentiating metabolic responders and nonresponders as defined by Weber et al. [82], early response assessment by [ F]-FDG-PET turned out to predict histopathologic response with a sensitivity of 77% and specificity of 86%, respectively. Lordick et al. [222] prospectively... 

Molecular risk biomarkers could detect systemic or local changes indicating that the carrier of this specific biomarker is at higher risk for disease development in the future. Examples include the presence of human papillomavirus in the cervix, which is associated with a higher risk for the development of cervical cancer, the association between Hdicohacterpylori and gastric cancer as well as EBV and nasopharyngeal carcinoma. The drawback of these markers is that they are not helpful for the detection of early disease. 

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