Canadian-Domestic Substances List

The higher, long-chain dimers as weH as the tetramer dehydroacetic acid are far more stable and can be handled safely. The alkylketene dimers (AKDs) are shipped to the paper industry in tank tmcks in the form of ready-to-use aqueous emulsions with a total soHds content of 12—25% and a guaranteed shelf life of 30 days, as they have good hydrolytic stabHity. In this form they are not combustible Hquids, and are Hsted in the Canadian Domestic Substances List. 

All eight PMBs are Hsted on the U.S. EPA s TSCA Inventory (May 1, 1994 ed.) and on the European Communities EINECS inventory (June 15, 1990). All but pentamethylbenzene are Hsted on the Canadian Domestic Substances List (DSL) (Apr. 6, 1994). Pentamethylbenzene is Hsted on the Canadian Nondomestic Substances List (NDSL) (Apt. 6, 1994) and as of July 1, 1994 was subject to New Substance Notification if manufactured in or imported into Canada. 

Vinyl chloride is Hsted as "ethene, chloro-" on the Toxic Substances Control Act (TSCA) inventory and on the Canadian Domestic Substances List (DSL). It is Hsted as "chloroethylene" on the European Inventory of Existing Commercial Chemical Substances (EINECS), bearing the identification number 2008 310 (149). 

Poly(vinyl chloride) is Hsted on the TSCA inventory and the Canadian Domestic Substances List (DSL) as ethene, chloro-, homopolymer [9002-86-2]. Because polymers do not appear on the European Community Commercial Chemical Substances listing or EINECS, poly(vinyl chloride) is listed through its monomer, vinyl chloride [75-01-4]. In the United States, poly(vinyl chloride) is an EPA hazardous air pollutant under the Clean Air Act Section 112 (40 CER 61) and is covered under the New Jersey Community Right-to-Know Survey N.J. Environmental Hazardous Substances (EHS) List as "chloroethylene, polymer" with a reporting threshold of 225 kg (500 lb). 

Macdonald, D., Breton, R., Sutcliffe, R., and Walker, J., Uses and limitations of quantitative structure-activity relationships (QS ARs) to categorize substances on the Canadian Domestic Substance List as persistent and/or bioaccumulative, and inherently toxic to non-human organisms, SAR QSAR Environ. Res., 13, 43-55, 2002. 

The Canadian Environmental Protection Act, 1999 (CEPA 1999) requires the Ministers of the Environment and Health to categorize the substances on the Canadian Domestic Substances List (DSL). The DSL contains 23 000 substances that are subject to categorization (i.e., prioritization). Generally the data selection process involves a search of the scientific literature and databases for quality experimental data for persistence, bioaccumulation potential and inherent toxicity to humans and nonhuman species. If acceptable data are not found, QSARs or other models are used to estimate the persistence, bioaccumulation, and aquatic toxicity of substances based on structure and physical - chemical properties. 

Common Data Source Approach. Another approach is to use a common source of data for benchmarking a set of chemicals. Examples of potential data sources include Material Safety Data Sheets (MSDSs) from product manufacturers, the Hazardous Substances Data Bank (HSDB), the Integrated Risk Information System (IRIS), the International Uniform Chemical Information Database (lUClID), the High Rroduction Volume Information System (HRVIS), the Organisation for Economic Cooperation and Development (OECD) Screening Information Dataset (SIDS), and the Canadian Domestic Substances list... 

Health Canada Proposal for Priority Setting for Existing Substances on the Domestic Substances List under the Canadian Environmental Protection Act, 1999 Greatest Potential for Human Exposure. This report describes a proposed priority setting process of existing substances in Canada. A stakeholder meeting was convened to discuss the Complex Exposure Model (comET). 

The Canadian new chemicals program uses two chemical inventories, the Domestic Substances List (DSL) and the Non-Domestic Substances List (NDSL). The DSL includes substances that were, between January 1, 1984, and December 31, 1986, in Canadian commerce, used for manufacturing purposes, or manufactured in or imported into Canada.17 It contains about 23,000 substances. One of the initiatives in the Canadian Environmental Protection Act, 1999 (CEPA, 1999) requires the Minister of the Environment and the Minister of Health to categorize (Section 73, CEPA 1999) and then if necessary, conduct screening assessments (Section 74, CEPA 1999) of substances listed on the DSL to determine whether they are toxic or capable of becoming toxic as defined in the Act. The NDSL is a list of substances not on DSL but in commerce elsewhere in the world.18 The NDSL contains more than 58,000 entries. 

Guidelines for the notification and testing of new substances chemicals and polymers pursuant to the new substances notification regulations of the Canadian Environmental Protection Act , 1993, Ministry of Supply and Services, Canada. Canada Gazette Extract, 26 January 1991, Domestic Substances List and Canada Gazette Part /, 5 September, 1992, pp.2735-2737. 

Canadian Provisional Domestic Substance list deflection temperature under load divinylbenzene... 

The Canadian Environmental Protection Act (CEPA) requires thar EC review the entire Canadian chemical inventory, the Domestic Substances list (DSL), for the purpose of identifying those substances which are toxic pursuant to CEPA. This analysis requires EC to determine which chemicals on the DSL are persistent and either bioaccumulative or inherently toxic. 

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