Calcium L- + -ascorbate

E 302 calcium L-ascorbate foods fat-containing cereal-based 0.2 g kg 1... 

C8H70-8-Ca +-2Hs0 Calcium L-ascorbate, dihydrate CAASCO, 01, 32 354... 

Acid Derivatives.—Calcium DL-glycerate, potassium D-glucarate, calcium L-ascorbate (comparison of two analyses), 2,3 4,6-di-0-isopropylidene-L-... 

Ci2Hi8CaOiar Calcium L-ascorbate dihydrate, 40B, 655 44B, 401 C12H180g, 4-Ethyl-6-di-0-acetyl-2,3-dideoxy-a-D-erythro-hex-2-eno-pyranoside, 45B, 466, 479... 

L-Ascorbic acid biosynthesis in plants and animals as well as the chemical synthesis starts from D-glucose. The vitamin and its main derivatives, sodium ascorbate, calcium ascorbate, and ascorbyl palmitate, are officially recognized by regulatory agencies and included in compendia such as the United S fates Pharmacopeia/National Formula (USP/NF) and the Food Chemicals Codex (FCC). 

The main sources of vitamin C are green vegetables and citrus fruit. Animal tissue contains vitamin C, mainly in the kidneys and liver. The level of vitamin C in food is rapidly reduced during cooking or storage due to oxidation or water dissolution. It is added to food as an antioxidant (with no specified limit on the level of use) or as a supplement (with a maximum recommended daily intake of 3000mg/day). The forms admitted are L-ascorbic acid (AA), L-ascorbyl 6-palmitate, sodium, calcium, or potassium L-ascorbate [403]. 

Ascorbic Acid and Ascorbic Acid Esters and Saits Vitamin C or ascorbic acid is widespread in nature but sparingly associated with fats of oils because of its hydrophilic nature (95). Ascorbic acid in the free form, salts of sodium and calcium, and esters of stearic and palmitic are commonly used as antioxidants in foods. Erythorbic acid is the D-isomer of naturally present L-ascorbic acid (Figure 10) and is often used as an antioxidant in dried fruits and a cure... 

Crystal structures of L-ascorbic acid varying from coarse to ultrafine powder constitute the major commercial product forms of the compound, followed by special coated and granulated forms. Sodium L-ascorbate is also produced in granular and powder forms. Limited production of other forms such as calcium ascorbate and ascorbyl palmitate depend on demand of these products in specialty use applications. 

Many vitamins are quite stable under normal processing conditions and present little or no stability problems in finished pharmaceutical products. These include biotin, niacin, niacinamide, pyridoxine, riboflavin, and a-tocopheryl acetate. Others that can present problems are ascorbic acid, calciferol, calcium pantothenate, cyanocobalamin, fola-cin, and retinyl esters. Overages above label claim are customarily added to vitamin formulations as a means of maintaining the claimed level of each vitamin for the expected shelf life of the products. The percent overage for a particular vitamin such as L-ascorbic acid will vary... 

P2, Z =2 Dx = 1.771, 1.773 R = 0.038 for 1,321 intensities, 0.036 for 2,283 intensities. The proton attached to 0-3 is that removed on salt formation. The ring is planar within 0.05 A (5 pm). The shapes of the side chains of the two ions are different, with 0-4-C-4-C-5-0-5 torsion angles of 56 and 170°, respectively. The other conformational angle of the side chain, 0-5-C-5-C-6-0-6, is 47° in both molecules. The calcium ion is eight-coordinated, in a distorted, square anti-prism, by six oxygen atoms from three L-ascorbate ions and by two water molecules. 

E302 L-Ascorbic calcium Synthetic salt Preservative, antioxidant Low possibility for stone formation in the kidneys Madrilene... 

Lutavit B6. See Pyridoxine HCI Lutavit B12. See Cyanocobalamin Lutavit C Cryst. See L-Ascorbic acid Lutavit Calpan Feed Grade. See Calcium D-pantothenate... 

Anoxomer L-Ascorbic acid Ascorbyl palmitate Ascorbyl stearate BHA BHT t-Butyl hydroquinone 3-t-Butyl-4-hydroxyanisole Calcium citrate Calcium disodium EDTA... 

Calcium oxalate monohydrate Sodium formate oxalic acid source Potassium oxalate oxidant, food L-Ascorbic acid oxidant, rocket fuels Perchloryl fluoride oxidant, selective... 

Vitamins may be assayed by means of microbial electrodes constructed from cells whose metabolic activity or growth is dependent on the vitamin assayed. Such microbial strains are well known from the commonly used microbiological assays. For instance, the assessment of thiamine was performed by means of yeast cells immobilized in a calcium al inatte membrane. The difference in oxygen consumption before and after incubation with thiamine in the sample is related to the thiamine content [269]. Similar biosensors have been worked out for nicotinic acid (with Lactobacillus arabinosa) [270], nicotine amide (with B. pumilus and E. coli) [271], and L-ascorbic acid (with Enterobacter agglomerans) [272]. 

Karpinska, T., Kawecki, Z., and Kandefer-Szerszen, M., 1982, The influence of ultraviolet irradiation, L-ascorbic acid and calcium chloride on the induction of interferon on human embryo fibroblasts. Arch. Immunol. Ther. Exp. 30 33. 

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