C-myc oncogene

Tavassoli, M., and S. Shall. 1988. Transcription of the c-myc oncogene is altered in spontaneously immortalized rodent fibroblasts. Oncogene 2(4) 337 15. 

Little CD, Nau MM, Carney DN et al. Amplifieation and expression of the c-Myc oncogene in human lung cancer eell lines. Nature 1983 306 194-196. 

Bartlett PF, Reid HH, Bailey KA, Bernard O (1988) Immortalization of mouse neural precursor cells by the c-myc oncogene. Proc Natl Acad Sci U S A 85 3255-3259... 

Hulia W, Kaliay E, Krugluger W, Peterlik M and Cross HS (1995) Growth control of human colon-adenocarcinoma-derived Caco-2 cells by vita-min-D compounds and extracellular calcium in vitro relation to c-myc-oncogene and vitamin-D-receptor expression. Int J Cancer 62 711-716. 

Bennett MR, Evan GI, Newby AC (1994) Deregulated c-myc oncogene expression blocks vascular smooth muscle cell inhibition mediated by heparin, interferon-y, mitogen depletion and cyclic nucletide analogues and induces apoptotic cell death. Circ Res 74 525-536... 

The application of telomerase needs to be studied with the potential deleterious effects of introducing hTERT in mind. Telomerase activation extends the life span of human mammary epithelial cell (HMEC) cultures while at the same time inducing lasting overexpression of c-myc oncogene. The relevance of telomerase in senescence is intensely debated. 

Cantharidin (2,3-dimethyl-7-oxabicyclo[2,2,1 ]heptane-2,3-dicarboxylic anhydride) as an antitumor agent A retrospective review 13CMD159. Cyclometallated iridium(III) complex with 2,2 -biquinoline N-donor hgand as a c-myc G-quadruplex stabiHzer and down-regulator of c-myc oncogene expression 13CMD576. 

Evan Gl, Lewis GK, Ramsay G, Bishop JM (1985) Isolation of monoclonal antibodies specific for the human c-myc oncogene product. Mol Cell Biol 75 3610-3616. 

Dewanjee MK, Ghafouripour AK, Kapadvanjwala M, Dewanjee S, Serafini AN, Lopez DM, Sfakianakis GN. Noninvasive imaging of c-myc oncogene messenger RNA with indium-111-antisense probes in a mammary tumor-bearing mouse model. J Nucl Med 1994 35 1054-1063. 

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