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Absorption buccal

Wagner, J. G. Sedman, A. J., Quantitation of rate of gastrointestinal and buccal absorption of acidic and basic drugs based on extraction theory, J. Pharmacokinet. Biopharm. 1, 23-50 (1973). [Pg.282]

Ho, N. F., Higuchi, W. I., Quantitative interpretation of in vivo buccal absorption of n-alkanoic acids by the physical model approach, /. Pharm. Sci. 1971, 60, 537-541. [Pg.440]

A knowledge of the buccal absorption characteristics of a chemical can be important in a case of accidental poisoning. Although an agent taken into the mouth will be voided immediately on being found objectionable, it is possible that significant absorption can occur before any material is swallowed. [Pg.454]

One of the most common in vivo methods used to assess the permeability of the buccal mucosa is the buccal absorption test of Beckett and Triggs [13]. In this test, a known volume of a drug solution is introduced into the oral cavity of a subject, who swirls it around for a specified period of time and then expels it. The subject then rinses his or her mouth with an aliquot of distilled water or buffer solution, and the expelled drug solution and rinse are combined and analyzed for drug content. The difference between the initial and final drug concentration in the solution is assumed to be the amount of drug taken up into the oral mucosa. [Pg.96]

Barsuhn CL, Olanoff LS, Gleason DD, Adkins EL, Ho NFH (1988) Human buccal absorption of flurbiprofen. Clin Pharmacol Ther 44 225-231... [Pg.103]

Beckett AH, Triggs EJ (1967) Buccal absorption of basic drugs and its application as an in vivo model of passive drug transfer through lipid membranes. J Pharm Pharmacol 19 31S-41S... [Pg.103]

Beckett AH, Moffat AC (1969) Correlation of partition coefficients in n-heptane-aqueous systems with buccal absorption data for a series of amines and acids. J Pharm Pharmacol 21 144S-150S... [Pg.104]

Beckett AH, Boyes RN, Triggs EJ (1968) Kinetics of buccal absorption of amphetamines. J Pharm Pharmacol 20 92-97... [Pg.104]

Coutel-Egros A, Maitani Y, Veillard M, Machida Y, Nagai T (1992) Combined effects of pH, cosolvent and penetration enhancers on the in vitro buccal absorption of propranolol through excised hamster cheek pouch. Int J Pharm 84 117-128... [Pg.104]

Davis BJ, Johnston A (1979) Buccal absorption of verapamil—evidence for membrane storage. Br J Clin Pharmacol 65 434P... [Pg.104]

Henry JA, Ohashi K, Wadsworth J, Turner P (1980) Drug recovery following buccal absorption of propranolol. Br J Clin Pharmacol 10 61-65... [Pg.105]

Ho NFH (1993) Biophysical kinetic modeling of buccal absorption. Adv Drug Del Rev 12 61-97... [Pg.105]

Kitano M, Maitani Y, Takayama K, Nagai T (1998) Buccal absorption through golden hamster cheek pouch in vitro and in vivo of 17/f-estradiol from hydrogels containing three types of absorption enhancers. Int J Pharm 174 19-28... [Pg.106]

McElnay JC (1990) Buccal absorption of drugs. In Swarbrick J, Boylan JC (eds.) Encyclopedia of Pharmaceutical Technology. Marcel Dekker, New York, pp 189-211... [Pg.107]

Oh CK, Ritschel WA (1990) Biopharmaceutic aspects of buccal absorption of insulin. Methods Find Exp Clin Pharmacol 12 205-212... [Pg.108]

Rathbone MJ (1991a) Human buccal absorption. I. A method for estimating the transfer kinetics of drugs across the human buccal membrane. Int J Pharm 69 103-108... [Pg.108]

Rathbone MJ (1991b) Human buccal absorption. II. A comparative study of the buccal absorption of some parahydroxybenzoic acid derivatives using the buccal absorption test and a buccal perfusion cell. Int J Pharm 74 189-194... [Pg.108]

Schumann W, Turner P (1978) Membrane model of the human oral mucosa as derived from buccal absorption performance and physicochemical properties of the beta-blocking drugs atenolol and propranolol. J Pham Pharmacol 30 137-147... [Pg.108]

Zhang J, Niu S, McJames S, Stanley T (1991a) Buccal absorption of insulin in an in vivo dog model—evidence of mucosal storage. Pharm Res 8 S—155... [Pg.111]

Figure 7.2 presents permeation across freshly isolated porcine buccal mucosa of caffeine and atenolol. Caffeine and atenolol are compounds with complete and poor human buccal absorption in vivo, respectively [10, 29],... [Pg.169]

Schumann W, and Turner P (1977) The buccal absorption of atenolol and propranolol, and their physicochemical characteristics. Br. J. Clin. Pharmacol. 4 655P-656P. [Pg.178]

Veuillez F, Kalia YN, Jacques Y, Deshusses J, and Buri PA (2001) Factors and strategies for improving buccal absorption of peptides. Eur. J. Pharm. Biopharm. 51 93-109. [Pg.180]

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Acids buccal absorption

Bases buccal absorption

Buccal

Buccal absorption advantages

Buccal absorption bioadhesion

Buccal absorption dosage form

Buccal absorption drug transport mechanism

Buccal absorption formulation development

Buccal absorption measurement

Buccal absorption oral mucosa

Buccal and sublingual absorption

Buccal cavity, absorption

Buccal cavity, absorption drugs

Buccal insulin absorption

Drug absorption buccal mucosa

Drugs buccal absorption

Nicotine buccal absorption

Peptides buccal absorption

Propranolol buccal absorption

Proteins, buccal absorption

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