Beta,-blocking drugs

Bailly D, Servant D, Blandin N, et al Effects of beta-blocking drugs in alcohol withdrawal a double-blind comparative study with propranolol and diazepam. Bio-med Pharmacother 46 419—424, 1992... 

Schumann W, Turner P (1978) Membrane model of the human oral mucosa as derived from buccal absorption performance and physicochemical properties of the beta-blocking drugs atenolol and propranolol. J Pham Pharmacol 30 137-147... 

Wright P. Ocular reactions to beta-blocking drugs. BMJ 1975 4 577. 

Beta-blocking drugs given chronically lower blood pressure in patients with hypertension (see Chapter 11). The mechanisms involved are not fully understood but probably include suppression of renin release and effects in the central nervous system. These drugs do not usually cause hypotension in healthy individuals with normal blood pressure. 

A final example of the use of this strategy to examine futile deacetylation comes from work on the beta-blocking drug practolol where a radio-labelled 13C/14C drug was dosed to rats and the urine profiled by HPLC with UV, radioactivity, NMR and MS-MS detection [61]. As shown by the structure below, practolol can be considered to be an analogue of paracetamol with a beta-blocker side-chain ... 

Beta-blocking drugs (eg, propranolol) may be used as antianxiety agents in situations such as performance anxiety. The sympathetic nervous system overactivity associated with anxiety appears to be satisfactorily relieved by the fblockers, and a slight improvement in the nonsomatic components of anxiety may also occur. Adverse central nervous system effects of propranolol include lethargy, vivid dreams, and hallucinations. 

M. S. Leloux and F. Dost, Doping analysis of beta-blocking drugs using HPLC, Chromatographia, 32 429 (1991). 

Gold MH, Holy AK, Roenigk HH Jr. Beta-blocking drugs and psoriasis. A review of cutaneous side effects and retrospective analysis of their effects on psoriasis. J Am Acad Dermatol 1988 19(5 Pt 1) 837-41. 

Goldsteins. Beta-blocking drugs and coronary heart disease. Cardiovasc Drugs Ther 1997 11 219-225. 

Laverdue B, Boulenger JP (1991) Medications beta-bloquantes et anxiete. Un interet therapeu-tique certain. [Beta-blocking drugs and anxiety. A proven therapeutic value.] L Encephale 17 481 92. 

Wilson, M.J. Ballard, K.D. Walle, T. Preparative resolution of the enantiomers of the beta-blocking drug atenolol by chiral derivatization and high performance liquid chromatography. J.Chromatogr, 1988, 431, 222-227... 

Your 55-year-old patient with asthma and glaucoma is to receive a beta-blocking drug. Regarding beta-blocking drugs... 

A. Tremor Physiologic and essential tremor are elinieally similar conditions characterized by postural tremor. They may be alleviated by beta-blocking drugs such as propranolol. Beta-blockers should be used with eaudon in patients with eongestive heart failure, a.sthma, diabetes, or hj oglycemia. 

SamiiK, Ciancioni C, Rottembourg J, Bisseliches F, Jacobs C. Severe hypoglycaemia due to beta-blocking drugs in haem odialysis patients. Lancet (1976) i, 545-6. 

Cubey RB, Taylor SH (1975) Ocular reaction to propranolol and resolution on continued treatment with a different beta-blocking drug. Br Med J 4 327-328 Dammin GJ, Nova JR, Rearden JB (1955) Hydralazine reaction case with L.E. cells ante mortem and post mortem and pulmonary renal splenic and muscular lesions of dissem-minated lupus erythematosus. J Lab Clin Med 46 806-809 Davies DM, Beedie MA, Rawlings MD (1975) Antinuclear antibodies during procainamide treatment. Br Med J 3 682-683... 

Rodgers, T., Leahy, D., and Rowland, M.(2005) Tissue distribution of basic drugs accounting for enantiomeric, compound and regional differences amongst beta-blocking drugs in rat. J. Pharm. ScL, 94, 1237-1248. 

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