Erythromycin Bromocriptine

Epoxypropyl)-2-methyl-5-nitroimidazole Ornidazole Ergocryptine Bromocriptine Erythromycin... 

Bromocriptine, erythromycin and terfenadine had to be omitted from this correlation because Absolv does not calculate the water solubilities of compounds with McGowan volumes, V, greater than 4.0. This is because the solubility training set used in Absolv, Eq. (6), does not contain compounds with V values greater than 4 hence predictive power for such compounds are not reliable. 

Drugs that may affect tacrolimus include nephrotoxic agents (aminoglycosides, amphotericin B, cisplatin, cyclosporine), antifungals, bromocriptine, calcium channel blockers, cimetidine, clarithromycin, danazol, diltiazem, erythromycin, methylprednisolone, metoclopramide, carbamazepine, phenobarbital, phenytoin, rifamycins, cisapride, chloramphenicol, metronidazole, nefazodone, omeprazole, protease inhibitors, macrolide antibiotics, fosphenytoin, and St. John s wort. 

Drugs that may increase sirolimus blood concentrations include the following Nicardipine, verapamil, clotrimazole, fluconazole, itraconazole, clarithromycin, erythromycin, troleandomycin, cisapride, metoclopramide, bromocriptine, cimetidine, danazol, HIV-protease inhibitors, cyclosporine, diltiazem, azole antifungals. 

Bromocriptine (Parl el) [Antiparkinsonian Agent/Dopamine Receptor Agonist] Uses Parkin on Dz, hyperprolactinemia, acromegaly, pituitary tumors Action Direct-acting on the striatal dopamine receptors X prolactin secretion Dose Initial, 1.25 mg PO bid titrate to effect, w/ food Caution [B, ] Contra Severe ischemic heart Dz or PVD Disp Tabs, caps SE X BP, Raynaud phenomenon (vasospastic disorder resulting in discoloration of the fmgers/toes), dizziness, N, hallucinations Interactions T Effects W/ erythromycin, fluvoxamine, nefazodone, sympathomimetics, antihypertensives X effects W/ phenothiazines, antipsychotics EMS Monitor BP may cause intolerance to EtOH OD May cause NA, severe hypotension give IV fluids symptomatic and supportive... 

BROMOCRIPTINE, CABERGOUNE ERYTHROMYCIN t bromocriptine and cabergoline levels Inhibition of metabolism Monitor BP closely and watch for early features of toxicity (nausea, headache, drowsiness)... 

Trade names Apo-Bromocriptine Bromed Cryocriptina Kripton Parilac Parlodel (Novartis) Pravidel Serocryptin Indications Amenorrhea, parkinsonism, infertility Category Dopamine receptor agonist Half-life initial 6-8 hours terminal 50 hours Clinically important, potentially hazardous interactions with erythromycin, lanreotide, pseudoephedrine, sympathomimetics... 

Preliminary study suggests that erythromycin markedly increases serum concentrations of bromocriptine. 

Eiythromycin markedly increases bromocriptine plasma levels, and a case of toxicity has been reported. Bromocriptine toxicity also occurred in a patient given josamycin. Clarithromycin increases cabeigoline levels, and erythromycin would be expected to interact similarly. Eiythromycin had no effect on lisuride levels. 

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