Breath aromatics

Studies in humans and animals have shown that Stoddard Solvent is readily absorbed through the lungs. In general, the aromatic components are likely to be more completely absorbed due to their higher blood/gas solubility. It is expected that volatile components or metabolites of Stoddard Solvent that have low blood solubility would be most easily excreted in exhaled breath. Aromatic components would be expected to be excreted primarily in urine as metabolites. 

Almost all of the biomedical research done in the 25 years following the liquid-breathing work was conducted with commercially available fluorocarbons manufactured for various industnal uses by the electrochemical Simons process (fluonnation in a hydrofluoric acid solution) or the cobalt fluoride process (fluori-nation with this solid in a furnace at about 200 C) These processes tended to yield many by-products, partly because they were, to some extent, free radical reactions and partly because it was difficult to easily achieve complete fluonnation Aromatic hydrocarbons gave better products with the cobalt tnfluonde [73] method, whereas saturated hydrocarbons yielded better products with fluonnation using diluted or cooled gaseous fluorine (Lagow) Incompletely fluormated matenal was either... 

Raman spectra obtained on concentrated protein solutions (ca. 20 mM) are dominated by contributions from the repeating amide group of the polypeptide backbone and from the sldechalns of aromatic amino acids (6). Phenylalanine and tryptophan exhibit particularly Intense ring breathing modes at 1006 and 1014 cm, respectively. An additional strong peak due to tryptophan Is typically observed at 760 cm ... 

Hydrophobic (Aromatic) Amino Acid Breath Test... 

Mine Safety Appliances Co. (MSA) manufactures potassium superoxide in the United States for use in self-contained breathing equipment. There are several published uses for potassium superoxide in organic chemistry, e.g., for oxidizing aromatic compounds and for initiating anionic polymerization. 

Azo compounds. These compounds exhibit stretching of the —N=N— bond giving rise to only weak absorption near 1600 cm-1, which is shifted to lower frequency by conjugation. In aromatic compounds the band is generally masked by the aromatic ring breathing vibrations. 

Fig. 6.12. A Typical CARS signal trajectory revealing the particle number fluctuations of 110-nm polystyrene spheres undergoing free Brownian diffusion in water. The epi-detected CARS contrast arises from the breathing vibration of the benzene rings at 1003cm 1. B Measured CARS intensity autocorrelation function for an aqueous suspension of 200-nm polystyrene spheres at a Raman shift of 3050 cm-1 where aromatic C-H stretch vibrations reside. The corresponding translational diffusion time, td, of 20 ms is indicated. (Panel B courtesy of Andreas Zumbusch, adapted from [162])...

For the intramolecular modes, Raman scattering allows us to observe many modes of g symmetry,47 among which the most intense are the completely symmetric modes of the aromatic skeleton 390 cm "1 for bending of C-C-C angles, and 1400 cm "1 for stretching of the C-C bonds (breathing mode). 

Polynuclear aromatic hydrocarbons (PAH s) are produced in most incomplete combustion processes. Examples are internal combustion engines, effluents from coal fired electricity generating plants, tobacco smoke, and from coking operations in steel and aluminum refineries, PAH s are also present in coal tar derived and coal tar containing products such as creosote and roofing pitch. They are found in the water we drink and the air we breathe, and are a ubiquitous component of our environment. 

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