Liquid breathing

Shortly after the liquid-breathing expenment [f] was published, the same liquid was used to perfuse an isolated heart from an animal [6], by intermittent perfusion with typical aqueous buffer and fluorocarbon Then Sloviter [7] showed that an emulsion of this fluorocarbon liquid, made by ultrasonication with an albumin solution, could sustain the life of the brain of a rat as well as or better than perfusing... 

Almost all of the biomedical research done in the 25 years following the liquid-breathing work was conducted with commercially available fluorocarbons manufactured for various industnal uses by the electrochemical Simons process (fluonnation in a hydrofluoric acid solution) or the cobalt fluoride process (fluori-nation with this solid in a furnace at about 200 C) These processes tended to yield many by-products, partly because they were, to some extent, free radical reactions and partly because it was difficult to easily achieve complete fluonnation Aromatic hydrocarbons gave better products with the cobalt tnfluonde [73] method, whereas saturated hydrocarbons yielded better products with fluonnation using diluted or cooled gaseous fluorine (Lagow) Incompletely fluormated matenal was either... 

Skin Water flush immed (solution/liquid) Breath Resp support... 

Exposure Routes, Symptoms, Target Organs (see Table 5) ER inh, Con (iiquid) SY Dizz, drow, asphy iiquid frostbite TO Resp sys, CNS First Aid (see Table 6) Eye Irr immed (liquid) Skin Water flush immed (liquid) Breath Resp support ... 

The high solubility of many gases, including oxygen, in fluorocarbons has led to these compounds being used as blood substitutes in cardiopulmonary machines and as potential carriers in liquid breathing. Tham et have recently measured the solubility of O2, N2, and CO2 in the three commercially available fluoro-ethers perfluoro-l,4-di-isopropoxybutane, perfluoro-1-isopropoxyhexane, and perfluorobutyl-perfluorotetrahydrofuran and noted... 

Can closed tanks for solids and liquids breathe during changes of filling level, ambient pressure or temperature Is the breather pipe properly dimensioned Can underpressure or ingress of air and humidity occur ... 

Military Specification MIL-A-27420, Air, Liquid Breathing, 4-30-70, Naval Publications and Forms Center, 5801 Tabor Ave., Attn. Customer Service, Code 1052, Philadelphia, PA 19120. 

Most organic solvents are flammable volatile liquids. Breathing their vapors can cause nausea or dizziness. Also avoid skin contact. 

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