Breast cancer combined modality treatment

Thomas E, Buzdar A, HortobagyiG, etal. Long-Term Follow Up of Stage III Breast Cancer-Combined Modality Treatment with Anthracycline Containing Chemotherapy (CT) The MD Anderson Experience (Meeting abstract). ProcAnnu Meet Am Soc Clin Oncol 1999 18 A284. 

A Surrogate Endpoint for Survival Combined Modality Treatment in Inflammatory Breast Cancer Concluding Remarks References... 

COMBINED MODALITY TREATMENT IN INFLAMMATORY BREAST CANCER... 

Buzdar AU, Singletary SE, Booser DJ, Frye DK, Wasaff B, Hortobagyi GN. Combined modality treatment of stage III and inflammatory breast cancer. M.D. Anderson Cancer Center experience. Surg Oncol Clin N Am 1995 4 715-734. 

Int J Radiat Oncol Biol Phys 19 1071-1075 Tsuji H, Ishikawa H, Yanagi T, et al (2007) Carbon-ion radiotherapy for locally advanced or unfavourably located choroidal melanoma a phase I/II dose-escalation study. Int J Radiat Oncol Biol Phys 67 857-862 Ueno NT, Buzdar AU, Singletary SE, et al (1997) Combined-modality treatment of inflammatory breast carcinoma twenty years of experience at M.D. Anderson Cancer Center. Cancer Chemother Pharmacol 40 321-329 Veyret C, Levy C, Chollet P, et al (2006) Inflammatory breast cancer outcome with epirubicin-based induction and maintenance chemotherapy ten-year results from the French Adjuvant Study Group GETIS 02 trial. Cancer 107 2535-2544... 

Melphalan is an antineoplastic drug, listed also as a Class I immunosuppressive agent (effective only when given prior to the immune stimulus) [1]. It is used for the treatment of multiple myeloma, ovarian carcinoma, tumors of the testes, chronic granulocytic leukemia, chronic lymphocytic leukemia, seminoma, Ewing s sarcoma, reticulum cell sarcoma, and thymoma [1,2]. Its use as an adjuvant to surgery in the management of primary breast cancer was one of the first illustrations of the therapeutic potential of combined modalities of treatment [3]. 

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