Botulinum toxin phenol

Glenn MB, Elovic E. Chemical denervation for the treatment of hypertonia and related motor disordrers phenol and botulinum toxin. J Head Trauma Rehabh 1997 12 40-62. 

Botulinum toxin often has to be used at the same time as a deep peel on patients with thick skins in order to limit the contractions of the orbicular muscle of the Kps and to improve/maintain results. The horizontal fold between the lower Kp and the prominence of the chin does not usuaUy respond weU to peels, even deep ones, ft can easily be filled in, however, together with the nasolabial folds 1-2 months after the phenol peel. 

Treating wrinkles phenol plus botulinum toxin... 

Full-face phenol (Lip Eyelid formula) (a) before and (b) 30 days after the peel. The combination of botulinum toxin and phenol work together on the forehead, crow s feet, frown lines and sometimes wrinkles on the upper lip. 

Expression lines on the forehead and between the eyebrows and crow s feet have a natural tendency to recur partially and rapidly, even after a phenol peel. A botulinum toxin injection before the peel stops expression lines imprinting themselves on the skin as it renews itself, and this combination is very satisfactory, improving results significantly. The botulinum toxin should be injected 1 week before the peel so that new collagen can be synthesized on an immobile dermis. 

The injection can also be given 8 days after the phenol peel, if not done beforehand. Injecting botulinum toxin during the post-peel period of erythema and edema increases the risk of the toxin moving as well as the risk of temporary cosmetic complications caused by the toxin. The duration of the toxin s effect does not seem to change much, however. 

Before (a) and after (b) a full-face phenol peel (Lip Eyelid formula) a combination of yellow skin, wrinkles, fine lines and lentigines in a patient who smokes. Thirty days after the peel the erythema is normal. The patient is not wearing any make-up. Botulinum toxin was injected 8 days before the peel (forehead, frown lines and crow s feet). 

The use of photosynthetic enzymes isolated from plants has been implemented in a toxicity monitor (LuminoTox, Lab Bell Inc., Shawinigan, Canada). This system can detect a range of compounds such as hydrocarbons, herbicides, phenols, polycyclic aromatic hydrocarbons (PAHs), and aromatic hydrocarbons. These enzymes have been coupled to screen-printed electrode and have been demonstrated to be able to detect triazine and phenylurea herbicides [79]. Other enzyme inhibitions have been used to detect biotoxins from plant, animals, bacterial, algae, and fungal species (e.g., ricin, botulinum toxins, mycotoxins, cyanobacterial toxins). However, since the identity and specificity of the above toxic compound can be very important during the analysis, other sensor systems such as immunosensors may be preferred to give a better indication to toxin type and identity than the use of enzyme inhibition tests. 

Yuxingcao injection, 772 muscle cramps eplerenone, 344 immunoglobulins, intravenous, 516 phenol, 381 muscle fasdculations suxamethonium, 221 muscle/joint pains naltrexone, 168 muscle rigidity morphine, 160 muscle spasms fenoflbrate, 724 rosuvastatin, 724 simvastatin, 724 muscle vein thrombosis polidocanol, 795 muscle weakness botulinum toxins, 226-7 musculoskeletal pain codeine, 152 cyclobenzaprine, 227 methylnaltrexone, 152 mutagenicity lamivudine, 456 methylphenidate, 5-6... 

In a retrospective study of single and multilevel injections of phenol, botulinum toxin, or both in children with chronic muscle spasticity, the local adverse effects were comparable with other previously reported studies. However, in contrast to previous studies, rare cases of dysesthesia (0.4%) were reported with phenol injections [72 j. 

In a retrospective study, Fu and colleagues analysed the utilisation and effectiveness of injectable spasticity medications used by the physiatry team at a referral-based tertiary cancer centre. The analysis of patient and injection characteristics was obtained from patients who had received botulinum toxin or phenol nerve block injection during the 5-year period. Out of the 3724 physiatry consultations, 20 (less than 1%) different cancer patients received a total of 54 total procedures. The results showed that the majority of patients (17/20, 85%) had a positive response to... 

A total of 10 of 20 patients received only one injection. Of these, 7 reported a positive response to the injected item. Those with only one injection tended to live farther away and died sooner. Only 4 of 54 injection procedures resulted in undesirable side effects (2 for phenol, 2 for botulinum toxin). And 9 of the 54 procedures occurred while the patients were on a chemotherapy protocol. All patients were injected at least lyear out from initial diagnosis. 

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