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Bone-derived growth factors

Bone formation and resorption are influenced by several protein factors. For example, IGF-I stimulates formation of bone, but EGF promotes breakdown.256 Additional bone-derived growth factors and morphogenetic factors also have been described.256 257 A cartilage-inducing factor has been identified as TGF-p.258... [Pg.1755]

BDGF Bone-derived growth factor emf Electromotive force... [Pg.963]

Meikle MC, Mak WY, Papiaoannou S, Davies EH, Mordan N, Reynolds JJ. Bone-derived growth factor release from poly(alpha-hydroxy acid) implants in vitro. Biomaterials 1993 14 177-83. [Pg.77]

Tissue growth factor, recombinant human platelet-derived growth factor, and a synthetic bone matrix... [Pg.941]

Human growth hormone (GHl, Fig. 1), epidermal growth factor (EGF), insnlin (INS), platelet-derived growth factor (PDGF), and many cytokines bind receptors that activate intracellular tyrosine kinase activity. The major isoform of GHl is a protein of 191 amino acids (22 KDa) that fnnctions in part to stimulate the growth of bone and internal organs in children. As shown in Fig. 1, the human growth hormone receptor (GHR), which is a member of the cytokine-hematopoietin receptor superfamily. [Pg.383]

Terek, R.M., Jiranek, W.A., Goldberg, M.J., Wolfe, H.J., Alman, BA. The expression of platelet-derived growth-factor gene in Dupuytren contracture. J. Bone Joint Surg. 1995 77 1 -9... [Pg.88]

Meikle, M.C. Papaioannou, S. Ratledge, T.J. Speight, P.M. Watt-Smith, S.R. Hill, P.A. Reynolds, J.J. Effect of poly D-lactide-co-glycolide implants and xenogeneic bone matrix-derived growth factors on calvarial bone repair in the rabbit. Biomaterials 1994, 15 (7), 513-521. [Pg.193]

What is a decoy receptor How does the decoy receptor osteoprotegerln block bone resorption Some tumors are characterized by excess production of platelet-derived growth factor (PDGF). How might a recombinant decoy receptor function as a chemotherapeutic agent for such a... [Pg.608]

Y.J. Park, Y.M. Lee, S.N. Park, S.Y. Sheen, C.P. Chung, S.J. Lee, Platelet derived growth factor releasing chitosan sponge for periodontal bone regeneration. Biomaterials 21 (2000) 153-159. [Pg.114]

Mast cells arise from bone marrow-derived progenitor cells that circulate as undifferentiated CD34+ mononuclear cells in the peripheral circulation. Subsequently, these undifferentiated CD34 cells migrate into tissue and mature under the influence of locally derived growth factors and cytokines. [Pg.111]

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See also in sourсe #XX -- [ Pg.1755 ]



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Bone growth

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