Blood oxygenators erythrocytes

Bone marrow is the spongy tissue inside the cavities of our bones. Bone marrow stem cells grow and divide into the various types of blood cells white blood cells (leukocytes) that fight infection, red blood cells (erythrocytes) that transport oxygen, and platelets that are the agents for clotting. 

The most important task of the red blood cells (erythrocytes) is to transport molecular oxygen (O2) from the lungs into the tissues, and carbon dioxide (CO2) from the tissues back into the lungs. To achieve this, the higher organisms require a special transport system, since O2 is poorly soluble in water. For example, only around 3.2 mb O2 is soluble in 1 L blood plasma. By contrast, the protein hemoglobin (Hb), contained in the erythrocytes, can bind a maximum of 220 mb O2 per liter—70 times the physically soluble amount. 

Riera, M., Fuster, J.F., and Palacios, L., 1991, Role of erythrocyte organic phosphates in blood oxygen transport in anemic quail. Am. J. Physiol. 260 R798-R803. 

Hemoglobin and myoglobin are the oxygen carrying proteins in all vertebrates. Hemoglobin, which is found in the blood packaged in red blood cells (erythrocytes), also serves to transport carbon dioxide and to some extent also hydrogen ions. 

A lowered blood oxygen tension serves as a stimulus for erythropoiesis. Oianges are detected by the kidney, which responds by releasing erythnqXMetin, a hor mone that stimulates erythrocyte production. 

The major types of mature blood cells are relatively short-lived and postmitotic, meaning they are no longer dividing. These mature blood cells are responsible for the functions of the hematopoietic system and include red blood cells (erythrocytes) that carry oxygen, granulocytes and monocytes that fight infections, and platelets that help clot the blood and aid wound healing. 

Hemoglobin is a globulin protein (globulins are a group of proteins, insoluble in water but soluble in diluted alkalies). Hemoglobin is a constituent of the red blood cells (erythrocytes) of vertebrates, which transport oxygen to... 

The most conspicuous use of iron in biological systems is in our blood, where the erythrocytes are filled with the oxygen-binding protein hemoglobin. The red color of blood is due to the iron atom bound to the heme group in hemoglobin. Similar heme-bound iron atoms are present in a number of proteins involved in electron-transfer reactions, notably cytochromes. A chemically more sophisticated use of iron is found in an enzyme, ribo nucleotide reductase, that catalyzes the conversion of ribonucleotides to deoxyribonucleotides, an important step in the synthesis of the building blocks of DNA. 

ERYTHROCYTES. Erythrocytes are biconcave diskshaped, blood cells (with pits or depressions in the center on both sides), the primary function of which is to transport hemoglobin, the oxygen-carrying protein. The biconcave shape of the erythrocyte provides a large surface volume ratio and thereby facilitates exchange of oxygen. The average diameter of erythrocytes is 7.5 pm, and thickness at the rim is 2.6 pm and in the center about 0.8 pm. The normal concentration of erythrocytes in blood is approximately 3.9-5.5 million cells per pL in women and 4.1-6 million cells per pL in men. The total life span of erythrocytes in blood is 120 days. 

SOD isolated from bovine liver or erythrocytes has been used medically as an anti-inflammatory agent. Human SOD has also been expressed in several recombinant systems, and is currently being evaluated to assess its ability to prevent tissue damage induced by exposure to excessively oxygen-rich blood. 

Erythrocytes Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing hemoglobin whose function is to transport oxygen, [nih]... 

Red blood cells RBCs. Cells that carry oxygen to all parts of the body. Also called erythrocytes. [NIH]... 

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