Blood glucose, monitoring

The U.S. market for dmgs to control blood glucose totals about 1 x 10 , equally divided between insulin and all other antidiabetic dmgs (33). Insulin sales ate expected to grow by about 10% annually, whereas the antidiabetic dmg market as a whole is expected to shrink by about 3%. The blood glucose monitoring market totals about 7.5 x 10 in the United States and is expected to grow at a rate of 10% annually. 

Urine testing has been widely used to monitor glucose levels in die past, but this metiiod has largely been replaced witii blood glucose monitoring. 

Carefully follow manufacturer s instructions because blood glucose monitoring devices vary greatly. 

PTSD Posttraumatic stress disorder SBGM Self blood glucose monitoring... 

Other forms of analytical investigations may also be applied, such as at-line analysis (discontinuous direct analysis of objects, e.g., noninvasive blood glucose monitoring) and trans-line analysis (remote sensing, teleanalysis). 

Fischbacher C, Jagemann K-U, Danzer K, MUller UA, Mertes B (1995) Non-invasive blood glucose monitoring by chemometrical evaluation ofNIR-spectra. 24th EAS (Eastern Analytical Symposium), Somerset, NJ, November 12-16... 

Danzer K, Fischbacher C, Jagemann K-U, Reichelt KJ (1998) Near-infrared diffuse reflection spectroscopy for non-invasive blood-glucose monitoring. LEOS Newslett 12(2) 9... 

Klonoff D.C., Noninvasive blood glucose monitoring, Diabetes Care 1997 20 (3) 433-437. 

Clinical utility takes the concept a step further and shows that the patient s medical outcome is favorably influenced by knowledge of the diagnostic test. An example would be that the tight insulin control that is only possible with frequent home blood glucose monitoring has a positive impact on delay of complications of diabetes. FDA does not require that a demonstration of clinical utility be performed in support of submissions but does... 

Q58 In d iabetes, blood glucose monitoring by the patient is of benefit ... 

Directive 98/79/EC on in vitro diagnostics (TVDs ) came into force on 7 June 2000 and is mandatory from 7 December 2003. This covers products such as pregnancy tests, blood glucose monitoring and tests for transmissible diseases. 

Use appropriate blood glucose monitoring to determine the therapeutic response and to identify the minimum effective dose for the patient. Thereafter, measure... 

Home/self blood glucose monitoring, HbAj,, signs and symptoms of hyper/hy-poglycemia, complete blood count, routine blood chemistry... 

Fineberg SE, Bergenstal RM, Bernstein RM, Laffel LM, Schwartz SL. Use of an automated device for alternative site blood glucose monitoring. Diabetes Care 2001 24(7) 1217-20. 

For blood glucose monitoring, it will generally be necessary to obtain linear sensor response in the range of 2-20 mM. In an air-saturated solution, the Michaelis constant (Km) for glucose will be 5-6 mM. This corresponds to the substrate concentration yielding half the maximum reaction rate velocity. The maximum rate would occur at a concentration of about 15 mM, leading to mostly nonlinear... 

Clemens AH, Chang PH, Myers RW. The development of biostator, a glucose controlled insulin infusion system (GCIIS). Hormone Metabolism Research Supplement Series (Blood Glucose Monitoring) 1977, 7, 23-33. 

Smart WH, Subramanian K. The use of silicon microfabrication technology in painless blood glucose monitoring. Diabetes Technology Therapeutics 2000, 2, 549-559. 

Maruo K, Oota T, Tsurugi M, Nakagawa T, Arimoto H, Hayakawa M, Tamura M, Ozaki Y, Yamada Y. Noninvasive near-infrared blood glucose monitoring using a calibration model built by a numerical simulation method trial application to patients in an intensive care unit. Applied Spectroscopy 2006, 60, 1423-1431. 

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