Bis 4-hydroxyphenyl propane

2400mg/kg mouse 3250mg/kg rat 4000mg/kg guinea pig 150mg/kg mouse 

Mildly irritant to the skin, however, severely irritant to the eyes. Ecotoxicity data are not yet available. 

The condensation of phenol (7.1.) with 1 mol acetone leads to the Bisphenol A which has little interest as a mi-crobicide. Its antifungal activity is not very distinctive the antibacterial efficacy is not worth a mention. 

Microbicide group (substance class) Chemical name Chemical formula Structural formula 

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The most common commercial polycarbonate [24936-68-3] is prepared from 2,2-bis (4-hydroxyphenyl)propane, that is, bisphenol A [80-05-7] and has the general stmcture ... 

As already indicated, the polycarbonates may be produced from a wide range of polyfunctional hydroxy compounds. In practice only the diphenyl compounds have proved of much interest and the only polycarbonate of commercial significance is derived from bis-phenol A 2,2-bis-(4-hydroxyphenyl) propane. 

Chemical Designations - Synonyms 2,2-Bis(4-Hydroxyphenyl)Propane p,p -Dihydroxy-... 

The most widely used monomer compd is 2,2-Bis (4-hydroxyphenyl)-propane or bisphenol-A. For a description of this monomer see Vol 2, B147-R- The properties of the polymer or resin comprised of this monomer are presented next ... 

To cold diionyl chloride (1.31 g, 11 mmol) in an ice-water bath, pyridine (10 mL) is added slowly for 10 min to keep the reaction temperature low. The reaction medium is stirred for 30 min. Then, a mixture of isophdialic acid (0.41 g, 2.5 mmol) and terephdialic acid (0.41 g, 2.5 mmol) in pyridine (10 mL) is added slowly for 10-20 min to control the reaction temperature. The cooling badi is then removed and the reaction mixture is stirred at room temperature for 20 min. 2,2-Bis(4-hydroxyphenyl)propane (bisphenol-A, 1.14 g, 5 mmol) in pyridine (10 mL) is added all at once to the mixture, and the whole solution is heated to 80°C (bath temperature) for 4 h. The resulting viscous solution is diluted with pyridine and poured into methanol to precipitate the polymer, which is washed in boiling methanol and dried. The inherent viscosity of polymer is 2.2 dL/g (determined in 60/40 phenol-1.1.2.2-tetrachloroethane at 30°C)... 

Experiment with addition of diphenyl carbonate Diphenyl terephthalate, 31.8 g (0.1 mol), 28.62 g (0.09 mol) of diphenyl isophthalate, and 2.37 g (0.011 mol) of diphenyl carbonate are polycondensed with 45.6 g (0.2 mol) of 2,2-bis(4-hydroxyphenyl)propane (bisphenol-A) under the preceding conditions. A slighdy brownish, extremely tough, noncrystalline polyester is obtained with an inherent viscosity equal to 0.56 dL/g. The softening point of the polyester is equal to 200°C and the melting range is 215-285°C. 

Bisphenol A, whose official chemical name is 2,2-bis(4-hydroxyphenyl)propane, is a difunctional monomer with two reactive hydroxyl groups, as shown in Fig. 20,2. It polymerizes svith dicarbonyl organic monomers, such as phosgene or diphenyl carbonate, which are illustrated in Fig. 20.3. During polymerization, shown in Fig. 20.4, the hydroxyl groups of the bisphenol A deprotonate in the presence of a base. After deprotonation, the oxygen atoms on the bisphenol A residue form ester bonds with the dicarbonyl compounds. The polymerization process terminates when a monohydric phenol reacts with the growing chain end. 

Determination of 2,2-bis(4-hydroxyphenyl)propane (bisphenol A) in food simulants... 

Raw Materials Important raw materials are bisphenol A (2,2-bis, 4-hydroxyphenyl propane) and epichlorohydrin. 

Both 2,2-bis(4-hydroxyphenyl)propane (BPA, bisphenol-A) and 2,2-bis(4-hydroxyphenyl)heptane (BP-5) were a gift from Dr M. Metzler (Kaiserlautern, Germany). Mono-, di-, tri- and tetrachlorinated BPA were a gift from Dr J.L. Vilchez (Granada, Spain). 

The reaction was repeated on a different polymer sample with the solid bis(chloroformate) of 2,2-bis(4-hydroxyphenyl)propane which resulted in the following increase in intrinsic viscosity of the polymer 0.28 to 0.54 dl/g. 

Bisphenol-A (BPA) or 2,2-bis(4-hydroxyphenyl)propane is one of the highest volume chemicals produced worldwide, with a production volume of approximately 3.8 million tons in 2006 [199]. BPA is mainly used as monomer in the production of polycarbonate and epoxy resins. Polycarbonate is a transparent polymer with a high impact resistance which can be used in different consumer goods such as reusable drinking bottles and food containers. Epoxy resins on the other hand are used as inner coating of food and drink cans. Release and exposure of... 

Synonyms BPA 4,4 -l-methylethylidene)-bisphenol 4,4 -isopropylidenediphenol 2,2-bis(4-hydroxyphenyl)propane p,p -dihydroxydiphenylpropane diphenylolpropane 4,4 -isopropylidenediphenol... 

Acetoacet-4-phenetidide, 5.9, 680 atomised almninimn, 5.7, >1.36kbar/s aluminium flake, 8.6, >1.36kbar/s almninimn-cobalt alloy, 6.25, 748 aluminium-magnesium alloy, 5.85, 680 almninimn-nickel alloy, 6.5, 680 aluminium stearate, 5.85, 680 benzoic acid, 6.85, 700 2,2-bis(4-hydroxyphenyl) propane, 5.5, 803 calcimn silicide, 5.85, 1.36 kbar/s calcimn stearate, 6.6, >680 cellulose nitrate, >17.4, >1.42 kbar/s 2-chlorobenzyfidenemalononitrile, 6.1, >680 comnarone-indene resin, 6.3, 748. 

Polycarbonates are polyesters of carbonic acid. The most important commercial polycarbonate is that based on 2,2 -bis(4-hydroxyphenyl)propane(bisphenol A) [Freitag et al., 1988 Sehanobish et al., 1996]. It has been synthesized by the reaction of the dihydric phenol with phosgene or by ester interchange with diphenyl carbonate ... 

The terms epoxy resin (EP) and ethoxyline resin are used to describe polyphenol derivatives and other compounds which resinify by ring opening of oxirane rings. The polyphenols are typically diphenylolmethane or bis henol A [2,2-bis(4-hydroxyphenyl)propane] the latter diol is obtained by the condensation of phenol and acetone. Bisphenol A, is the most widely used phenol for epoxy resin production. 

As shown in Scheme 7, the polymerization of bis(4-fluorophenyl) phenyl-phosphine oxide (BFPO) with bisphenols [XIII] was carried out, and thermal properties of the obtained polyethers [XIV-A (ffinh = 0.63 dl/g) and XIV-B i)inh = 0.48 dl/g)] were studied by DSC and TG (12). In this study, 2,2-bis(4-hydroxyphenyl) propane and 4,4 -dihydroxybiphenyl were used as compounds XIII s. 

The carbonylation oxidative polycondensation of bisphenol, 2,2-bis(4-hydroxyphenyl)propane, with transition metal-based catalysts, which yields the respective aromatic polycarbonate, is of high potential interest [6] ... 

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