Biosensors self-assembled

Jia J, Wang B, Wu A, Cheng G, Li Z, Dong S. A method to construct a third-generation horseradish peroxidase biosensor self-assembling gold nanoparticles to three-dimensional sol-gel network. Anal Chem 2002 74 2217-... 

Sequence-specific biosensor, 183, 185 Selectivity, 92, 143, 147, 155 Selectivity coefficient, 143 Self-assembled monolayers, 39, 118 Selenium, 85 Sensor, 171 Silver halide, 159 Simulation, 35... 

Chaki NK, Vijayamohanan K. 2002. Self-assembled monolayers as a tunable platform for biosensor applications. Biosens Bioelectron 17 1-12. 

Zhong X, Yuan R, Chai Y, Liu Y, Dai J, Tang D (2005) Glucose biosensor based on self-assembled gold nanoparticles and double-layer 2d-network (3-mercaptopropyl)-trimethoxy-silane polymer onto gold substrate. Sensor Actuator B 104 191-198... 

Medintz, I.L., Clapp, A.R., Mattoussi, H., Goldman, E.R., Fisher, B., and Mauro, J.M. (2003) Self-assembled nanoscale biosensors based on quantum dot FRET donors. Nat. Mater. 2, 630-638. 

To fulfill both the requirement of CFME for the practical applications and the necessity of Au substrate to assemble so-called promoters to construct the third-generation biosensor, Tian el al. have combined the electrochemical deposition of Au nanoparticles (Au-NPs) onto carbon fiber microelectrodes with the self-assembly of a monolayer on these Au-NPs to facilitate the direct electron transfer of SOD at the carbon fiber microelectrode. The strategy enabled a third-generation amperometric 02 biosensor to be readily fabricated on the carbon fiber microelectrode. This CFME-based biosensor is envisaged to have great potential for (he detection of 02" in biological systems [158],... 

T. Wink, S.J. van Zuilen, A. Bult, and W.P. van Bemekom, Self-assembled monolayers for biosensors a tutorial review. Analyst 122, 43R-50R (1997). 

F. Frederix, K. Bonroy, W. Laureyn, G. Reekmans, A. Campitelli, W. Dehaen, and G. Maes, Enhanced performance of an affinity biosensor interface based on mixed self-assembled monolayers of thiols on gold. Langmuir 19, 4351-4357 (2003). 

J.C. Vidal, J. Espuelas, E. Garda-Ruiz, and J.R. Castillo, Amperometric cholesterol biosensors based on the electropolymerization of pyrrole and the electrocatalytic effect of Prussian-Blue layers helped with self-assembled monolayers. Talanta 64, 655 (2004). 

Moreover, it has been demonstrated that CNTs promote the direct electrochemistry of enzymes. Dong and coworkers have reported the direct electrochemistry of microperoxidase 11 (MP-11) using CNT-modified GC electrodes [101] and layer-by-layer self-assembled films of chitosan and CNTs [102], The immobilized MP-11 has retained its bioelectrocatalytic activity for the reduction of H202 and 02, which can be used in biosensors or biofuel cells. The direct electrochemistry of catalase at the CNT-modified gold and GC electrodes has also been reported [103-104], The electron transfer rate involving the heme Fe(III)/Fe(II) redox couple for catalase on the CNT-modified electrode is much faster than that on an unmodified electrode or other... 

S.G. Wang, R. Wang, P.J. Sellin, and Q. Zhang, DNA biosensors based on self-assembled carbon nanotubes. Biochem. Biophys. Res. Commun. 325, 1433-1437 (2004). 

We will discuss here applications of polyelectrolyte-modified electrodes, with particular emphasis on layer-by-layer self-assembled redox polyelectrolyte multilayers. The method offers a series of advantages over traditional technologies to construct integrated electrochemical devices with technological applications in biosensors, electrochromic, electrocatalysis, corrosion prevention, nanofiltration, fuel-cell membranes, and so on. 

These two examples show how emulsion-based magnetic colloids can become the essential elements for two apparently very different issues. In fact, this section introduces the basics of using superparamagnetic emulsion-based colloids, and their spontaneous self-assembling ability under a field, as new biosensors. The... 

These conditions are met in most practical situations, in micro- and even nanobiodevice applications. For instance, the high density of DNA molecules is required to increase the sensitivity of the device long DNA molecules are commonly (but not exclusively) used as target molecules in e.g., biosensors, microarrays and microPCR devices single DNA species used as targets translate in lack of complementarity and most substrates, (e.g., glass, polymers) for micro/nanobiodevices are amorphous. The critical difference between the self-assembled and amorphous DNA layers, which leads to the polymerlike character of the latter, is the lack of complementarity between adjacent strands. Still, as with polymers, the DNA chains have to have a consider-... 

During the end of the 20th century, a surge in the development of significantly advanced techniques has advanced nanoscience and technology in the development of self-assembly structures—micelles, monolayers, vesicles—biomolecules, biosensors, and surface and colloidal chemistry. In fact, the current literature indicates that there is no end to this trend regarding the vast expansion in the sensitivity and level of information. 

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