Biofunctionalization surface

The prepared porous nanocrystalline Ti-6A1-4V, Ti-15Zr-4Nb and Ti-6Zr-4Nb alloys with electrochemically biofunctionalized surface could be a possible candidate for hard tissue implant applications. 

Fig. 14.5 Surface chemistry The OFRR glass surface is biofunctionalized with 3APS. Then biorecognition molecules are immobilized using a cross linker...

C. Baquey, F. Palumbo, M.C. Porte-Durrieu, G. Legeay, A. Tressaud, R. d Agostino, Plasma-treatment of expanded PTFE offers a way to a biofunctionalization of its surface, NIM Nucl. Instmm. Methods Phys. Res. B 151 (1999) 255-262. 

FIGURE 8.6 Schematic representation of a new transducer for biosensor application based on a three-dimensional IDEA. Binding of molecules to the chemically modified and biofunctionalized transducer surface induces important conductivity changes between the electrodes, which can be monitored. (From Ram6n-Azcon, J. et al. 2008. Biosens. Bioelectron. 23 1367-1373. With permission.)... 

Sim FIR, Wark AW, Lee HJ (2010) Attomolar detection of protein biomarkers using biofunctionalized gold nanorods with surface plasmon resonance. Analyst 135 2528-2532... 

Although the fabrication and characteristics (material, size, biocompatibility, and others) of the desired SERS-encoded particles strongly depend on each specific application, all of them share some common requirements (a) the presence of an optical enhancer, (b) the addition of the SERS code, and (c) protection with a silica or polymer of the SERS code from leaching while providing a suitable surface for biofunctionalization [26, 27]. 

Both biomolecule doping and entrapment are likely to maintain CP biofunctionality for a longer period than if the biological molecules are adsorbed to the polymer surface postprocessing. Adsorption relies on ionic interactions at a material surface which dynamically alters when placed in a biological environment. The presence of molecules with stronger affinities for either the target molecule or the CP will result in displaeement of the biomolecule from the CP surface. 

Sun, X.Y., Shankar, R., Borner, H.G., Ghosh, T.K. and Spontak, R.J. 2007. Field-driven biofunctionalization of polymer fiber surfaces during electro spinning. Adv. Mater. 19 87-91. 

Kwak, K.A., Jyoti, M.A., Song, H.Y., 2014. In vitro and in vivo studies of three dimensional porous composites of biphasic calcium phosphate/poly s-caprolactone effect of biofunctionalization for bone tissue engineering. Applied Surface Science 301, 307—314. 

Arroyo-Hemandeza M, Martm-Palma RJ, Perez-Rigueiro J, Garcia-Ruiz JP, Garcia- Fierro JL, Martmez-Duart JM (2003) Biofunctionalization of surfaces of nanostructured porous silicon. Mater Sci Eng C 23 697... 

There are also many methods used for biofunctionalization of PSi surfaces. However, we will not discuss them. One can find this information, for example, in review papers prepared by Salonen and Lehto (2008). 

Direct attachment of proteins and peptides to the Qdot surface is based on two types of Qdot surface protein interactions dative thiol-bonding between Qdot surface sulfur atoms and cysteine residues and metal-affinity coordination of histidine (HIS) residues to the Qdot surface Zn atoms (Fig. 17.3(c)). The Weiss group demonstrated the former by using phytochelatin-related peptides to cap CdSe/ZnS (core/shell) Qdots, providing not only surface passivation and water solubility, but also a point of biochemical modification. Using peptides for both dispersion and biofunctionalization represents a new class of rationally designed multifunctional biological cap. ... 

Figure 4.6 (a) Synthesis of functional POC prepolymers POC-N3 and POC-Al (b) cartoon illustration of a new class of citrate-based biodegradable clickable elastomers (CABEs) with greatly improved mechanical strength and easily clickable surface for biofunctionalization (c) mechanical properties of cBPLP-Ser, cBPLP-Ser-N3, cBPLP-Ser-Al, and cBPLP-click (cBPLP-Ser-N3, Al) polymers (d) mechanical properties of CUPE, CUPE-N3, CUPE-Al, and CUPE-cUck (CUPE-N3, Al) polymers. The polymers used in (c) and (d) were cross-linked at 100 °C for 3 days. 

Although the desired extent of enzymatic hydrolysis of PET should be limited to the material surface for the purpose of biofunctionalization of the materials, considerable weight losses can be obtained following prolonged treatment with... 

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