Organosilica surface biofunctionalization

The optimal fusion of surface and internal biofunctionalization of silica nanoparhcles can lead to the creation of useful multifunctional nanoparticles. Although several reviews [8-10] have detailed the advances in biofunctionalization of inorganic siUca nanoparhcles, none of these has summarized recent developments in this area, such as ORMOSIL and funchonal organosilica nanoparhcles. In the following section we describe both surface and internal biofunchonalizahon strategies for various types of inorganic sihca and organosilica nanoparhcles. 

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