Beta-naphthylamine

Chemical Reactivity - Reactivity with Water No reaction Reactivity with Common Materials No reactions Stability During Transport Stable Neutralizing Agents for Acids and Caustics Not pertinent Polymerization Polymerization is accelerated by heat and exposure to oxygen, as well as the presence of contamination such as iron rust. Iron surfaces should be treated with an appropriate reducing agent such as sodium nitrate, before being placed into isoprene service Inhibitor of Polymerization Tertiary butyl catechol (0.06 %). Di-n-butylamine, phenyl-beta-naphthylamine andphenyl-alpha-naphthylamine are also recommended. 

Secondary aromatic amines, such as phenyl beta-naphthylamine. have been used as antioxidants in elastomers, but the preferred antioxidants for plastics have been 2,6-disubstituted and 2,4,6-trisubstituted phenols. These hindered phenols serve as chain transfer agents with the macroradicals which are produced by the degradation of polymers. 

Sorahan, T. Pope, D. (1993) Mortality study of workers employed at a plant manufacturing chemicals for the rubber industry 1955-86. Br. J. ind. Med., 50, 998-1002 Sorahan, T., Hamilton, L. Jackson, J.R. (2000) A further cohort study of workers employed at a factory manufacturing chemicals for the rubber industry, with special reference to the chemicals 2-mercaptobenzothiazole (MBT), aniline, phenyl-beta-naphthylamine and o-toluidine. Occup. environ. Med., 57, 106-115... 

Rubber antioxidants are commonly of an aromatic amine type, such as dibeta-naphthyl-para-phenylenediamine and phenyl-beta-naphthylamine. Usually, only a small fraction of a percent affords adequate protection. Some antioxidants arc substitute phenolic compounds (butylatcd hydro -vamsole, di-tert-butyl-para-cresol, and propyl gallate). 

Formulas for emulsion polymerization also include buffers, free radical initiators, such as potassium persulfate (KiSiOs), chain transfer agents, such as dodecyl mercaptan (G sSTT). The system is agitated continuously at temperatures below 100°C until polymerization is essentially complete or is terminated by the addition of compounds such as dimethyl dithiocarbamate to prevent the formation of undesirable products such as cross-linked polymers. Stabilizers such as phenyl Beta-naphthylamine are added to latices of elastomers. 

Sudborough (8) has succeeded in forming addition compounds with alpha and beta naphthylamine and alpha trinitrotoluene. These reactions take place at moderate temperatures in alcoholic solutions. 

Case, R. A., Hosker, M. E., Me, D. D., and Pearson, J. T. (1954). Tumours of the urinary bladder in workmen engaged in the manufacture and use of certain dyestuff intermediates in the British chemical industry. I. The role of aniline, benzidine, alpha-naphthylamine, and beta-naphthylamine. Br J Ind Med 11, 75-104. 

Hueper began work in November 1934 as chief pathologist of what was named the Haskell Laboratory. In experiments on dogs, he was able to show that beta-naphthylamine, and not other chemicals used in the plant, produced bladder tumors similar to those observed in the diseased employees. This finding, published in 1938 in the Journal of Industrial Hygiene and Toxicology, was a landmark in cancer research, the first experimental demonstration that a synthetic organic chemical causes cancer. 

Stavric, B., Klassen, R., and Miles, W. (1979) Gas-liquid chromatographic-mass spectrometric determination of alpha- and beta-naphthylamines in FD C Red No. 2 (amaranth). J. Assoc. Off Anal. Chem., 62, 1020-1026. 

OTHER COMMENTS beta-Naphthylamine is an extremely toxic chemical in any of its physical forms, such as flake, dust, liquid, or vapor may be fatal if absorbed through skin, if inhaled, or swallowed personnel should be completely protected against physical contact with this chemical this chemical has formerly been used in the manufacture of dyes and as an antioxidant in rubber. 

Methyl acetate, tech. s beta-Naphthylamine, tech. 1 l(Sat92°C)... 

J-add n. Fusion product of beta-naphthylamine-3,6-bisulfonic acid with caustic. Used in the manufacture of dyes. Abo known as 2-amino-5 naphthol-7-sulfonic add and 6-amino-1-naphthol-3-sulfonic acid. 

Does the facility have any of the following 4-nitrobiphenyl, alpa-Napthylamine, Methyl Chloromethyl Ether, 3,3 -Dichlorobenzidine, bis-Chlormethyl Ether, beta-Naphthylamine, Benzidine, 4-Aminodiphenyl, Ethyleneimine, beta-Propiolactone, 2-Acetylaminofluorene, 4-Dimethylaminoazobenzene, N-Nitrosodimethylamine, and Vinyl Chloride ... 

Hansen AM, Omland O, Poulsen OM, et al. (1994) Correlation between work process-related exposure to polycyclic aromatic hydrocarbons and urinary levels of alpha-naphthol, beta-naphthylamine and i-hydroxypyrene in iron foundry workers. Int Arch Occup Environ Health 65 385-394... 

The OSHA regulation 29 CFR 1910.1003 pertains to solid or liquid mixtures containing less than 0.1 percent by weight or volume of 4-nitroWphenyl, methyl chloromethyl ether, bis-chloromethyl ether, beta-naphthylamine, benzidine, or 4-aminodiphenyl, and solid or liquid mixtures containing less than 1.0 percent by weight or volume of alpha-naphthylamine, 3,3 -dichlorobenzidine (and its salts), ethyleneimine, beta-propiolactone, 2-acetyIaminofluorene, 4-dimethylaminoazobenzene, or N-nitrosodimethylamine. 

Dry sweeping and dry mopping are prohibited for 4-nitrobiphenyl, alpha-naphthylamine, 3,3 -dichlorobenzidine (and its salts), beta-naphthylamine, benzidine, 4-aminodiphenyl, 2-acetylaminofluorene, 4-dimethylaminoazobenzene, and N-nitrosodimethylamine. 

Employees exposed to 4-nitrobiphenyl alpha-naphthylamine 3,3 -dichloroben-zidine (and its salts) beta-naphthylamine benzidine 4-aminodiphenyl 2-acetylaminofluorene 4-dimethylaminoazobenzene and N-nitrosodimethylamine shall be required to wash hands, forearms, face, and neck upon each exit from the regulated areas, close to the point of exit, and before engaging in other activities. 

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