Benzylammonium chloride

Note According to several studies performed in the USA, it seems that fbenzalkonium chloride where the alkyl group R contains only 12 C-atoms (e.g. dodecyl benzylammonium chloride) is effective against the growth of Cryptosporidium spp. 

R)-1,1 -Bi-2-naphthol was prepared by resolution employing the N-benzylammonium chloride salt of (-)-cinchonidine to form separable diastereomeric clathrate complexes. Hu, Q-S. Vitharama, D. Pu, L. Tetrahedron Asymmetry 1995, 6, 2123. 

Hydrogen peroxide Ammonium persulfate 5-Methyl-2-mercaptobenzimidazole Benzylammonium chloride... 

To a suspension of 5-methyl-2-mercaptobenzimidazole (36 g, 0.2 mole), 2-chloromethyl-3,5-dimethyl-4-nitropyridine hydrochloride (47.4 g, 0.2 mole) and triethyl benzylammonium chloride (5 g) in a dichloromethane (500 ml) was added dropwise a solution of NaOH (17.6 gm, 0.44 mole) in water (30 ml). The addition was exothermic and the temperature was observed to rise to 40°C with reflux of dichloromethane - the reaction mixture was stirred for further 6 hours at ambient temperature and filtered. The cake was washed with water and dried in vacuum oven to yield 55.8 g of cream color product. Yield 81.1% melting point 124°-128°C. 

Benzylic quaternary salts react with hot dimethyl sulfoxide (DMSO) to give benzaldehyde. For example, benzylammonium chloride gives 60% benzaldehyde plus 24% benzylmethylamine and 5% benzyldimethylamine. 

DODECYL DIMETHYL BENZYLAMMONIUM CHLORIDE see BEMOOO DODECYLDIMETHYL(2-PHENOXYETHYL)AMMONIUM BROMIDE see... 

TETRADECANOL, mixed isomers see TBY500 n-TETRADECOIC ACID see MSA250 TETRADECYL ALCOHOL see TBY500 TETRADECYL DIMETHYL BENZYLAMMONIUM CHLORIDE see TCA500... 

The conventional methods (sodium hydride in dimethylformamide or triethyl-benzylammonium chloride under phase-transfer conditions) resulted in the formation of considerable amounts (13-48%) of the diethylated product. 

Alkyl-dimethyl-benzylammonium chlorides are constituents of many disinfectants because of their antibacterial activity. 

Fig. 5-45. Separation of an alkyl-dimethyl-benzylammonium chloride (Benzalkon A). - Separator column IonPac NS1 (10 pm) eluent (A) 0.02 mol/L HC1 / acetonitrile (50 50 v/v), (B) 0.02 mol/L HC1 / acetonitrile (20 80 v/v) gradient linear, from 30% B to 100% B in 20 min flow rate 1 mL/min detection UV (215 nm) injection volume 50 pL solute concentration 100 mg/L of the raw material.

A Darzens reaction has been used to generate /rons-epoxides <05SL842>. Reaction of electron deficient p-substituted benzylammonium chlorides with benzaldehyde provides the trans-epoxide 46 in excellent to moderate yield as a 99 1 mixture of trans. cis epoxides. 

Two-phase titration is usually less sensitive to interference from other foreign (nonsurfactant) species. When applied to anionic surfactant systems, two-phase titration is primarily used for the analysis of alkyl sulfates and sulfonates. Typical titrants in these applications are solutions of cetylpyridinium bromide, cetyltrimethylammonium bromide, and benzyldimethylalkyl (C12 or C14) ammonium chloride. The most accurate results are, however, obtained with p-tert-octyl-phenoxy-ethoxy-ethyl-dimethyl-benzylammonium chloride, also known under the commercial name of Hyamine 1622. The structure of Hyamine 1622 is shown in Fig. 11-32,a. 

AI3-14906 Ammonium, benzyltriethyl-, chloride Benzenemethanaminium, N,N,N-triethyl-, chloride Benzyl triethyl ammonium chloride Benzyltriethyl-ammonium chloride BTEAC EINECS 200-270-1 Sumquat 2355 TEAC TEBA TEBAC Triethyl-benzylammonium chloride N,N,N-Triethylbenzene-methanaminium chloride. Quaternary ammonium salt solvent for cellulose gelling Inhibitor in polyester resins intermediate In chemical manufxturing. Also used as a fibre dyeing auxilliary and phase transfer catalyst. Solid mp = 185° soluble in H2O (170 g/100 ml). Hexcel Janssen Chimica Zeeland Chem. Inc. 

Pyridylazo)resorcinol 4-(2-Pyridylazo)resorcinol + Tetradecyldimethyl-benzylammonium chloride 4-(2-Pyridylazo)resorcinol + Hydrogen peroxide Cobalt Nitroso-R salt... 

Figure 12. Plots of C vs, A predicted by the model when a surface aggregation process occurs. Curves were calculated from Eqs. (43) using the parameters given in text at the following In p.. x values, (1) -3, (2) -2, (3) -I, (4) 0, (5) 1, Inset Experimental C vs, E plots of the interface between an HME and a 0.1 M Na2S04 solution of lO" M Tween 80", recorded using 2 mV s" potential scan rate. Experimental data were reprinted from J. Electroaml. Chem., 356, S. Sotiropoulos el ai. Interfacial Micellization of Cetyl-Dimethyl-Benzylammonium Chloride and Tween-80" at the Hg/Electrolyte Solution Interface, p, 225, Copyright 1993, with permission from of Elsevier Science.

Oxidation of benzylammonium bromides. A few years ago Traynelis and Ode noted that benzylammonium chlorides are oxidized to carbonyl compounds in low to fair yields when heated in DMSO. The reaction proceeds more readily and in higher yield (50-85%) with benzylammonium bromides. The reaction... 

Recently, the Baran group discovered a mild abnormal Chichibabin pyridine synthesis using benzylammonium chloride as the amine source and Yb(OTf)3 as the catalyst to form pyridinium 173 instead of 174 in their... 

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