Benzenethiol sodium salt

Benzenethiol, sodium salt EINECS 213-224-0 HSDB 5771 Sodium benzenethiolate Sodium phenylmercap-tide Sodium phenylsulfide Sodium phenylthiolate Sodium thiophenate Sodium thiophenolate Sodium thio-phenoxide Sodium thiophenylate Thiophenyl sodium salt. 

Reaction of benzenethiol sodium salt with 3,5-dichlorotrifluoropyridine leads to substitution first at the 4-position, than at the 2-position, and finally at the 6-position in 3,4,3-trichlorodifluoropyridine (278) substitution occurs first at the 2-... 

These intermediates with benzyhnagnesinm bromides gave 2-benzyl-2/7-azirines 8 in 50-80% yields, bnt potassinm phthahmide and sodium salt of benzenethiol converted them into the corresponding azirines 9 and 10 in good yields (equation 4). Similar Neber-type cyclization of a-hthio oxime ethers to highly reactive azirines was recently reported. ... 

Dithioalkoxo- and dithiophenoxo-niobium(V) trichlorides [MCl3(SR)2] were obtained from NbCl5 and thiols and benzenethiol respectively.240 The synthesis of tris(benzenedithiolato) complexes was accomplished by reaction of the appropriate metal amide with a mixture of the dithiol and its sodium salt in THF. The structures of (AsPh4)[M(S2C6H4)3]241""243 showed the... 

Benzotriazol-l-yl)-2//-azirines 847, obtained by treatment of oximes 846 with tosylchloride and aqueous KOH, were reacted with benzylmagnesium bromide or 4-methylbenzylmagnesium bromide in the presence of zinc chloride and gave 2-benzyl-2//-azirines 848. Potassium phthalimide and the sodium salt of benzenethiol converted the 2-(benzotriazol-l-yl)-2//-azirines 847 into novel 2//-azirines 849 and 850 (Scheme 211) <2003JOC9105>. 

Benzaldehyde, 100, 105, 154, 175, 336 Benzamide, 320 Benzene, 134, 154, 198, 286 Benzenesulfenyl chloride, 182 Benzenesulfinic acid sodium salt, 18 Benzenesulfonamide, 18 Benzenesulfonyl azide, 17—18 Benzenesulfonyl bromide, 18 Benzenesulfonyl chloride, 17 N-Benzenesulfonylformimidic acid ethyl ester, 18-19 Benzenethiol, 182 Benzhydrol, 238 Benzil, 312 Benzimidazole, 126 2,1-Benzisothiazole, 290 Benzobicyclo[2.2.2]octadiene, 46 Benzocyclobutadiene, 227 Benzohydroquinones, 60 Benzoic acid, 175... 

Quinoxaline-2-thione is readily converted into 2-hydrazinoqmnoxaline on treatment with hydrazine hydrate, and 3-hydrazinoquinoxaline-2-thione is readily hydrolyzed (2.5 M HCl at 70°) to quinoxaline-2,3-dione. The sodium salt of quinoxaline-2-thione has been S-alkylated with a wide range of alkyl halides to give 2-quinoxalinyl sulfides,but attempts to carry out a parallel reaction with p-nitrochlorobenzene failed. p-Nitrophenyl-2-quinoxalinyl sulfide (5) can however be prepared by reaction of 2-chloroquinoxaline with the sodium salt of p-nitro-benzenethiol. ... 

This method, using ethanethiolate, has been extended to esters. The cleavage of methyl esters by lithium propanethiolate in HMPA, an 8 2 reaction, has been reported. The lithium salt reacts very much faster than the sodium salt. The benzenethiolate and propanethiolate anions have... 

In the former case, the dibromo- or dichloro-substituted arene is reacted with cuprous or sodium thiolates to give vicinal thioethers, which can be reductively dealkylated, for example with Na/NH3, to give the dithiols.63 Alternatively, benzenethiol is reacted with ra-BuLi, and the resulting lithiated product is made to react with elemental sulfur to give the 1,2-dithiolate salt. 

Interaction of substituted arenediazonium salts with potassium O. O-diphenylphosphorodithioates gave a series of solid diazonium salts which decomposed explosively when heated dry [10], The unique failure of diazotised anthranilic acid solutions to produce any explosive sulfide derivatives under a variety of conditions has been investigated and discussed [6]. Preparation of diaryl sulfides from interaction of diazonium and thiophenoxide salts led to violent explosions, attributed to presence of some arenediazo sulfide during subsequent distillation of the diaryl sulfides. Precautions are detailed [11]. A safe method of preparation of diaryl sulfides from diazonium tetralluoroborates and sodium benzenethiolate in DMF is now available [12],... 

A comparison of the suitability of solvents for use in Srn 1 reactions was made in benzenoid systems46 and in heteroaromatic systems.47 The marked dependence of solvent effect on the nature of the aromatic substrate, the nucleophile, its counterion and the temperature at which the reaction is carried out, however, often make comparisons difficult. Bunnett and coworkers46 chose to study the reaction of iodoben-zene with potassium diethyl phosphite, sodium benzenethiolate, the potassium enolate of acetone, and lithium r-butylamide. From extensive data based on the reactions with K+ (EtO)2PO (an extremely reactive nucleophile in Srn 1 reactions and a relatively weak base) the solvents of choice (based on yields of diethyl phenylphosphonate, given in parentheses) were found to be liquid ammonia (96%), acetonitrile (94%), r-butyl alcohol (74%), DMSO (68%), DMF (63%), DME (56%) and DMA (53%). The powerful dipolar aprotic solvents HMPA (4%), sulfolane (20%) and NMP (10%) were found not to be suitable. A similar but more discriminating trend was found in reactions of iodobenzene with the other nucleophilic salts listed above.46 Nearly comparable suitability of liquid ammonia and DMSO have been found with other substrate/nucleophile combinations. For example, the reaction of p-iodotoluene with Ph2P (equation (14) gives 89% and 78% isolated yields (of the corresponding phosphine oxide) in liquid ammonia and DMSO respectively.4 ... 

The sulfonation reaction is reversible and benzenesulfonic acid may be desulfonated by treatment with dilute acid at 150 °C. The group can be displaced by fusion of its salt with sodamide to give the corresponding amine, with sodium hydroxide to give the phenol, sodium cyanide to give the nitrile, and potassium hydrogen sulfide to give the benzenethiol (Scheme 5.10). 

The thiol (SH) group is introduced by reaction with potassium ethyl xanthate followed by acid hydrolysis. The phenylsulfanyl (phenylthio, SPh) group results from reaction with benzenethiolate ion. Sodium disulfide, Na2S2, yields diaryl disulfides. The arsonic acid group is introduced using Bart s reaction, in which a diazonium salt is reacted with sodium arsenite in the presence of a Cu(II) salt (Scheme 8.23). 

Pyridinethiol esters are readily reduced with Sodium Boro-hydride in the presence of isopropanol. Activation of 2-pyridinethiol esters with lodomethane allows for mild trapping with alcohols or benzenethiol, yielding esters or thiolesters. In these cases the use of iodomethane avoids the need for thiophilic silver or mercury salts and allows for transthiolesterification. 

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