Benzene sulfonic chloride

The aromatic sulfonyl chlorides which have no a-hydrogen and thus cannot form sulfenes give acylic sulfones. Thus 1-piperidinopropene on reaction with benzene sulfonyl chloride (9J) gave 2-benzenesulfonyl-l-piperidinopropene (153). Similarly the enamine (28) reacts with p-toluene-sulfonyl chloride to give the 2-p-toluenesulfonylcyclohexanone (154) on hydrolysis (/OS). 

A plugging material with 2-furaldehyde-acetone monomer and silicone oligomers has been described [1099]. The components for this material are shown in Table 18-1. The 2-furaldehyde-acetone monomer can contain mono-furfurylidene-acetone and difurfurylidene-acetone. The hardener can be iron chloride, benzene-sulfonic acid, hexamethylene diamine, or polyethylene polyamine. The plugging stone has improved strength, elastic-deformation, and anticorrosion and adhesion properties. 

In recent years, a variety of aryl boronic acids are commercially available, albeit in some cases they may be expensive for large scale purposes. During our work in the mid-1990 s boronic acid (II) was not commercially available and so two different protocols were used to prepare this acid. The first approach involved the transmetallation with n-butyl lithium of aryl bromide (I) and trapping the lithio species generated with trialkyl borate followed by an acid quench. Aryl bromide (I) is easily prepared by reaction of o-bromobenzenesulfonyl chloride with 2-propanol in the presence of pyridine as a base. The second approach was a directed metallation of isopropyl ester of benzene sulfonic acid (VII), to generate the same lithio species and reaction with trialkyl borate. The sulfonyl ester is prepared by reaction of 2-propanol with benzenesulfonyl chloride. From a long-term strategy the latter approach is... 

The acetylium ion is the strongest acid species in the acetic anhydride system, and acetyl fluoborate, which is a good conductor in liquid sulfur dioxide, is a strong acid in acetic anhydride. Acetyl fluoborate, chloride, thiocyanate, and benzene sulfonate may all be titrated as acids in acetic anhydride using sodium acetate, a strong base in that system. 08 The neutralization reaction is ... 

Nickel benzene sulfonate, 7.5 g/L, and triamine tolylphenyl methane chloride, 5-10 mg/L 212,000 5.0... 

The same compound is also obtained together with aminodiazobenzene, when benzene diazonium chloride or sulfonate reacts with benzamid-oxime 101). When heated in dilute mineral acid, XXVI readily loses NH3 to yield diphenyloxadiazole. 

Mannitol hexanitrate is obtained by nitration of mannitol with mixed nitric and sulfuric acids. Similarly, nitration of sorbitol using mixed acid produces the hexanitrate when the reaction is conducted at 0—3°C and at —10 to —75°C, the main product is sorbitol pentanitrate (117). Xylitol, ribitol, and L-arabinitol are converted to the pentanitrates by fuming nitric acid and acetic anhydride (118). Phosphate esters of sugar alcohols are obtained by the action of phosphorus oxychloride (119) and by alcoholysis of organic phosphates (120). The 1,6-dibenzene sulfonate of D-mannitol is obtained by the action of benzene sulfonyl chloride in pyridine at 0°C (121). To obtain 1,6-dimethanesulfonyl-D-mannitol free from anhydrides and other by-products, after similar sulfonation with methane sulfonyl chloride and pyridine the remaining hydroxyl groups are acetylated with acetic anhydride and the insoluble acetyl derivative is separated, followed by deacetylation with hydrogen chloride in methanol (122). Alkyl sulfate esters of polyhydric alcohols result from the action of sulfur trioxide—trialkyl phosphates as in the reaction of sorbitol at 34—40°C with sulfur trioxide—triethyl phosphate to form sorbitol hexa(ethylsulfate) (123). 

Benzene sulfonyl chloride may be made by the action of phosphorus pentachloride upon benzene sulfonic acid or its salts 1 by the action of phosphorus oxychloride upon the salts of benzene sulfonic acid 2 by the action of chlorosulfonic acid upon benzene 3 by the action of chlorosulfonic acid upon the... 

Drum dryers potatoes, cereals, buttermilk, skim milk, dextrins, yeasts, instant oat meal, polyacylamides, sodium benzoate, propionates, acetates, phosphates, chelates, aluminum oxide, m-disulfuric acid, barium sulfate, calcium acetate-arsenate-carbonate-hydrate-phosphate, caustic, ferrous sulfate, glue, lead arsenate, sodium benzene sulfonate, and sodium chloride... 

The importance of MP can be related to the physical state of the substance under the conditions of Draize test. In this study, it was assumed that chemicals with a MP less than or equal to 37°C would exist as liquids in the test procedure and that, in general, liquids would be more likely than solids to cause corrosion and irritation. The results confirm that there is indeed a relationship between physical state and the potential for acute skin toxicity. The fact that some solids are corrosive or irritant may relate to the fact that their MPs are not much higher than 37°C and that they exist as wax-like substances, which are more capable of penetrating into the skin than are solids with higher MPs. For example, carvacrol, and thymol, which are both irritant and corrosive, have predicted MPs of 38°C and 38.1°C, respectively. In the case of other solids, such as benzene sulfonyl chloride (MP = 61°C), the corrosive response may be due to a more toxic derivative (e.g., benzene sulfonic acid). 

Benzonitrile (1) Toluene + NH3 (2) Sodium benzene sulfonate + NaCN (3) Benzene diazonium chloride + NaCN... 

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