1.3- dimethoxy-benzene

H.42) Benzene, 1,4-dimethoxy-, 1,4-dimethoxybenzene, hydroquinone dimethyl ether, quinol dimethyl ether, p-methoxyanisole [150-78-7] FEMA 2386... 

Benzenedimethanamine Benzene-1,3-dimethaneamine. See m-Xylylenediamine Benzene, 1,3-dimethoxy-. See m-Dimethoxybenzene Benzene, 1,4-dimethoxy-. Seep-Dimethoxybenzene Benzene, m-dimethoxy-. See m-Dimethoxybenzene... 

Synonyms Anisole, p-methoxy- Benzene, 1,4-dimethoxy- 1,4-Dimethoxybenzene Dimethyl ether hydroquinone Dimethyl hydroquinone Dimethylhydroquinone ether DMB DMHQ HQDME Hydroquinone dimethyl ether p-Methoxyanisole Quinol dimethyl ether Classification Aromatic ether Definition Obtained by methylation of hydroquinone using dimethyl sulfate and alkali Empirical CsHio02 Formula C6H4(OCH3)2... 

Fig. 13. Dependence of apparent propagation rate constant on living end concentration showing triple ion contribution styrene-n-butyllithium-benzene-dimethoxy-ethane, 25° C, DME content (vol-%) from the top 45, 40, and 30%. Reproduced, with permission, from Ise, Hirohara, Marino, Takaya, and Nakayama Presented at the 17th Discussion Meeting of High Polymers, October, 1968, Matsuyama,...

Table 4. Dissociation and reactivity of lithium salt of living polystyrene in benzene-dimethoxy ethane mixtures at 25...

Synonyms 1,1,1 -Trichloro-2,2-bis(p-methoxyphe-nyl)-ethane l,l -(2,2,2-Trichloroethylidene)bis(4-methoxy-benzene) Dimethoxy-DT DMDT ENT 1716 Higalmetox Methoxychlore Marlate Met-hoxy-DDT OMS 466 Prentox Marlate Met-ox Chemform... 

SYNONYMS 1,1 -(2,2,2-T richloroethy lidene)bis(4-methoxy-)benzene, dimethoxy-... 

Diederich F, Jonas U, Gramlich V, Herrmann A, Ringsdorf H and Thilgen C 1993 Synthesis of a fullerene derivative of benzo[18]crown-6 by Diels-Alder reaction complexation ability, amphiphilic properties, and x-ray crystal structure of a dimethoxy-1,9-(methano[1, 2]benzomethano)fullerene[60] benzene clathrate Helv. Chim. Acta 76 2445-53... 

The acetal can also be cleaved with DDQ (CH2C12, H2O, 66% yield) to afford the monobenzoate. Treatment of a 3,4-dimethoxybenzyl ether containing a free hydroxyl with DDQ (benzene, 3 A molecular sieves, rt) affords the 3,4-dimethoxy-benzylidene acetal. ... 

B. (l-Azido-3,3-dimethoxy-l-propenyl)benzene. In a 2-1., one-necked, round-bottomed flask equipped with a magnetic stirrer and powder funnel are placed 156 g. (0.45 mole) of the iodoazide from Part A and 1500 ml. of anhydrous ether. The solution is stirred and cooled in an ice-salt bath (— 5° to 0°), and 62 g. (0.55 mole) of potassium <-butoxide (Note 6) is added. The powder funnel is then replaced by a calcium chloride drying tube and the mixture is stirred for 4 5 hours at 0°. At the end of this time 350 ml. of water is added while the mixture is still cold. The ethereal layer is then separated and washed with three 350-ml. portions of water and dried over magnesium sulfate. The solvent is removed with a rotary evaporator without heating, leaving 67-75 g. (68-76%) of (l-azido-3,3-dimethoxy-l-propenyl)-benzene as a dark oily liquid (Note 7). This material can be used without further purification for Part C (Note 8). 

The authors repeated the experiment with two, more strongly retained, solutes m-dimethoxy benzene and benzyl acetate. These solutes were found to elute at (k ) values of 10.5 and 27.0 respectively on a silica column operated with the same mobile phase. The results obtained are shown as similar curves in Figure 13. The m dimethoxy benzene, which eluted at a (k ) of 10.5, also failed to displace any ethyl acetate from the silica gel even when more than 0.5 g of solute resided on the silica surface. Consequently, the m-dimethoxy benzene must have also interacted with the surface by a sorption process. 

A solution of 50 grams of N-(a-methylhomoveratryl)-3-methoxy-4-ethoxyphenylacetamide, prepared as set out above, in 200 cc of benzene, is treated with 8 cc of phosphorus oxychloride. The mixture is refluxed for about 3 hours, cooled and then is shaken with a solution composed of 15 grams of sodium hydroxide dissolved in 60 cc of water. The aqueous layer is removed, and the benzene solution is washed with water. The washed benzene solution is dried over anhydrous magnesium sulfate, filtered and evaporated to dryness. The low-melting solid residue is 6,7-dimethoxy-3-methyl-1-(3 -methoxy-4 -ethoxybenzyl)-dihydroisoquinoline base. 

To a solution of 50 grams of 6,7-dimethoxy-3-methyl-T(4 -ethoxy-3 -methoxybenzyl)-dihy-droisoquinoline base in 200 ml of dry benzene are added 150 ml of decalin, and the mixture is distilled until its temperature reaches 180°C. 1.5 grams of 5% palladium on carbon are then added. The mixture is stirred under reflux for about 6 hours to dehydrogenate the dihydroisoquinoline. On cooling, the reaction mixture is diluted with petroleum ether and the precipitated 6,7-dimethoxy-3-methyl-1-(3 -methoxy-4 -ethoxybenzyl)-isoquinoline is filtered off and recrystallized from dilute ethanol. 

Katsuya et al. [5 published the oxidative coupling (agent copper(II) chloride/ aluminum chloride) of electron-rich benzene derivatives such as 2,5-dimethoxy-benzene to poly(2,5-dimethoxy-1,4-phenylene) (2). The resulting polymer is only soluble in concentrated sulfuric acid, and is fusible at 320r C. Ueda et al. 16] described the coupling of the same monomer with iron(III) chloride/aluminum chloride. The polymers obtained by the authors were not thoroughly para-linked. 

The highly electrophilic 1,3,5-triazinylnitrene generated by photolysis of 2-azido-4,6-dimethoxy-l,3,5-triazine (24) does, however, bring about ring expansion of benzene to l-(4,6-dimethoxy-1,3,5-triazin-2-yl)-1//-azepine (25) in moderate yield.168... 

The addition of alkyllithium, lithium dialkylcuprates and lithium trialkylzincates to either ( )-(2-nitroethenyl)benzene or E)- -nitropropene in the presence of the nonracemic chiral solvent, ( + )-(S,S)-2,3-dimethoxy-Af,AhA, iV -tetramethyl-l,4-butanediamine, gave adducts in low enantiomeric excess (15-28%) as determined by HNMR35. 

Ether, chloromethyl methyl [Methane, chloromethoxy-], 97 Ethylamine, dusoptopyl- [ 2-Propanamme, Af-ethyl-Af-(l-methylethyl)-], 59 Ethylamine, 2-(3,4-dimethoxyphenyl)-[Ben-zeneethanamme, 3,4-dimethoxy-], 5 Ethylene, 1,1-diphenyl- [Benzene, 1,1 -ethenylidenebis-], 32 Ethylene, tetramethyl- [2-Butene, 2,3-dimethyl-], 35... 

Phenol ethers show some, admittedly low, reactivity towards diazonium ions and also undissociated phenols (see Sec. 12.7). An instructive example of the reactivity of phenol ethers was reported by Ronaldson (1981). He found that 1,2-dimethoxy-benzene (veratrole) does not react with the 4-nitrobenzenediazonium ion, but the azo coupling product is formed when the more electrophilic 2,4-dinitrobenzenediazo-nium ion is used. 

The reaction of 1-alkoxynaphtalenes with copper (II) bromide in benzene produced a mixture of 4-bromo-1-alkoxynaphtalenes and 4,4 -dialkoxy-l,l -binaphtyls. For instance, the reaction of 1-methoxynaphtalene 4 with copper(II) bromide in refluxing benzene for 2 h. gave a mixture of 4-bromo-1-methoxy-naphtalene 5 (47 %) and 4,4 -dimethoxy-l,l -binaphtyl 6 (45 %). In contrast, in similar reaction using alumina-supported copper(II) bromide at 30°C, only dimerization occurred and no brominated compounds were obtained. 

A mixture of 1-methoxynaphtalene (0.95 g, 6 mmol) and alumina-supported copper(II) bromide (6 g) in benzene (30 ml) was stirred at 30°C for 1 h. The rnixmre was filtered and the spent reagent was washed several times with hot benzene. Hexane was added to the combined filtrates, which was concentrated, to precipitate 4,4 -dimethoxy-l,r-binaphtyl (0.82 g, 87 %), mp 254-255°C (from hexane-benzene (lit. 252-254°C (ref. 15)). 

In contrast to the dihalogens, there are only a few spectral studies of complex formation of halocarbon acceptors in solution. Indeed, the appearance of new absorption bands is observed in the tetrabromomethane solutions with diazabicyclooctene [49,50] and with halide anions [5]. The formation of tetrachloromethane complexes with aromatic donors has been suggested without definitive spectral characterization [51,52]. Moreover, recent spectral measurements of the intermolecular interactions of CBr4 or CHBr3 with alkyl-, amino- and methoxy-substituted benzenes and polycyclic aromatic donors reveal the appearance of new absorption bands only in the case of the strongest donors, viz. Act = 380 nm with tetramethyl-p-phenylendiamine (TMPD) and Act = 300 nm with 9,10-dimethoxy-l,4 5,8-... 

Reaction of 2-cyanomethylpyridine with iV-(l-aryl-l-chloro-2,2,2-trifluoroethyl)-iV -(4-methylphenyl)carbodiimides, and with (1,1,2,2,2-pentachloro- and l,l-dichloro-2,2,2-trifluoroethyl)isocyanates or A-methoxycarbonyl-l,2,2,2-tetrachloro-, — l-chloro-2,2-trifluoroacetaldehyde imines afforded 3-aryl-4-cyano-l-(4-methylphenyl)imino-3-trifluoromethyl-2,3-dihydro-17/-pyrido[l,2-f]pyrimidines and 4-cyano-3-trichloro-, 4-cyano-3-trifluoro-17/-pyrido[l,2-4pyrimidin-l-ones, respectively <2004CHE47>. Refluxing 2-cyanomethylpyridine and iV-(l-aryl-l-chloro-2,2,2-trifluoroethyl)isocyanates in benzene furnished l-aryl-4-cyano-l-trifluoromethyl-l,2-dihydro-3//-pyrido[l,2-4pyrimidin-3-ones. However, when the solution of the isocyanate was added dropwise to the solution of 2-cyanomethylpyridine, and the reaction mixture was then treated with NEt at room temperature, the isomeric 3-aryl-4-cyano-3-trifluoromethyl-2,3-dihydro-l//-pyr-ido[l,2-dpyrimidin-l-ones were obtained. Reaction of l-(acetyl- and benzoylmethylene)-6,7-dimethoxy-l,2,3,4-tetra-hydroisoquinolines with PhCONCS yielded 1-acetyl-, 1 -benzoyl-9,10-dime thoxy-3-pheny 1-6,7-dihydro-2//-pyrimido[6,l- ]isoquinoline-2-thiones <2003SL2369>. 

Tetramethyl-1,4-dimethoxy-benzene Polycyclic aromatic hydrocarbons 1-46 (g) 8.06 (0... 

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