B-cell receptor signaling

Herishanu Y, Perez-Galan P, Liu D et al (2011) The lymph node microenvironment promotes B-cell receptor signaling. NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia. Blood 117 563-574... 

McCaig AM, Cosimo E, Leach MT et al (2011) Dasatinib inhibits B cell receptor signalling in chronic lymphocytic leukaemia but novel combination approaches are required to overcome additional pro-survival microenvironmental signals. Br J Haematol 153(2) 199-211... 

Ohnishi, K., and F. Melchers. 2003. The nonimmunoglobulin portion of lambda5 mediates cell-autonomous pre-B cell receptor signaling. Nat. Immunol. 4 849-856. 

Moreover, in this study, a large number of proteins involved in the signal transduction were identified. Indeed B-cell receptor signaling proteins (numerous membrane receptors, kinase proteins) implied in the signal transduction was detected. This com-plexome identified in the microparticles is reported on Figure 7. The proteins in grey were identified in our study. 

Kono H, Kyogoku C, Suzuki T et al 2005 FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling. Hum Mol Genet... 

Imaging B-Cell Receptor Signaling by Single-Molecule Techniques... 

Nitschke, L. Carsetti, R. Ocker, B. Kohler, G. Lamers, M. C., CD22 is a negative regulator of B-cell receptor signalling. Curr Biol 1997, 7, (2), 133-43. 

Jin, L. McLean, P. A. Neel, B. G. Wortis, H. H., Sialic acid binding domains of CD22 are required for negative regulation of B cell receptor signaling. JExp Medim, 195, (9), 1199-205. 

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