Azelaic Acid from Vegetable Feedstock via Oxidative Cleavage with Ozone or Oxygen

Azelaic Acid from Vegetable Feedstock via Oxidative Cleavage with Ozone or Oxygen 

Azelaic acid (AA), 1,9-nonanedioic acid or heptane-1,7-dicarboxylic acid, is used in manifold application areas. AA is offered in the pharmaceutical field for the treatment of acne and rosacea due to its antibacterial effect [1,2]. However, AA is much more widely applied as a monomer for the production of polymers such as alkyd resins, polyamides, and impact-proof polyesters or for the synthesis of plasticizers, lubricants, lithium complex greases, corrosion inhibitors, dielectric fluids, heat-transfer fluids, metal to glass fluxes, emulsion breakers, waxes, tobacco sheet plasticizers, hot-melt coatings and adhesives, water-soluble coating resins, hydraulic fluids, fungicides, insecticides, and so on [3-7]. 

Main renewable feedstock for the production of AA is oleic acid (OA), which is cleaved to A A and pelargonic acid (PA) by ozonolysis [7]. Although various catalysts and oxidants [5, 9] for the cleavage of C18 fatty acids and their derivatives to AA have been described in the scientific literature, these have not been used 

Liquid Phase Aerobic Oxidation Catalysis Industrial Applications and Academic Perspectives, 

First Edition. Edited by Shannon S. Stahl and Paul L. Alsters. 

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I 20 Azelaic Acid from Vegetable Feedstock via Oxidative Cleavage with Ozone or Oxygen CH3(CH2)7 (CH2)7C00R... 

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