Avlosulfon - Dapsone

Trade names Avlosulfon Dapson Dapson-Fatol Maloprim (Combination) Protogen Sulfona Indications Leprosy, dermatitis herpetiformis Category Antibiotic Antimycobacterial Half-life 10-50 hours... 

Although dapsone (Avlosulfon) is most often used as an antimicrobial agent, it has important antiinflammatory... 

Although dapsone (Avlosulfon) was once used in the treatment and prophylaxis of chloroquine-resistant P. falciparum malaria, the toxicities associated with its administration (e.g., agranulocytosis, methemoglobinemia, hemolytic anemia) have severely reduced its use. 

Dapsone (Avlosulfon) is a member of a class of chemical agents known as the sulfones. Dapsone is especially effective against M. leprae and is used with rifampin as the primary method of treating leprosy. Dapsone appears to exert its antibacterial effects in a manner similar to that of the sulfonamide drugs that is, dapsone impairs folic acid synthesis by competing with PABA in bacterial cells. Primary adverse effects associated with dapsone include peripheral motor weakness, hypersensitivity reactions (skin rashes, itching), fever, and blood dyscrasias, such as hemolytic anemia. 

Dapsone Avlosulfone , Eporal , Diphenasone , Udolac Dinoprostone... 

Aoedapsone AI3-08087 4-Aminophenyl sulfone p-Aminophenyl sulfone Aniline, 4,4 -sulfonyldi- Araldite HT Araldite HT 976 Avlosulfon Avlosulfone Aviosulphone Benzenamine, 4,4 -sulfonyibis- Bis(4-aminophenyl) sulfone Bls(4-aminoplienyl)sulphone BRN 0788065 CCRIS 192 Croysulfone Croysulphone DADPS Dapson Dapsona Dapsone 4,4 -Dapsone ... 

Sulfonylbisbenzenamine, 9CI. 4,4 -Sulfonyldianiline, SCI. Bis(4-aminophenyl) sulfone. Dapsone, BAN, USAN, INN. Avlosulfon. Diaphenylsulfone. Metabolite C. NSC 6091. Other proprietary names [80-08-0]... 

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