Auditory nerve damage

Q7 has an increased risk of neonatal haemolysis during the third trimester Q8 may cause vestibular or auditory nerve damage Q9 should be stopped at least 2 days before delivery Q10 consists of a folate antagonist that poses a teratogenic risk... 

CHRONIC HEALTH RISKS auditory nerve damage hearing loss central nervous system depression dermatitis about the fingernails and along the side of the fingers may alter genetic material. 

SY Irrit eyes, nose, throat head, dizz, drow corn inflamm, blurred vision, lac, photo derm possible auditory nerve damage, hearing loss CNS depres... 

All aminoglycosides are associated with auditory or vestibular nerve damage, especially during the second and third trimesters. The risk is greatest with streptomycin and is lower with gentamicin and tobramycin. 

The aminoglycosides decrease the fidelity of translation by binding to the 30S subunit of the ribosome. This permits the formation of the peptide initiation complex but prohibits any subsequent addition of amino acids to the peptide. This effect is due to the inhibition of polymerization as well as to the failure of tRNA and mRNA codon recognition. Aminoglycosides are ototoxic (i.e., may produce partial deafness), damaging the auditory nerve. Kanamycin is less toxic. Since aminoglycosides are concentrated in the kidney, they may occasionally cause kidney damage. 

Platinum-based chemotherapeutics induced hair cell death in rodents, albeit in variable patterns. In guinea pig, mice, and rat, cisplatin caused hearing loss that correlated to the loss of hair cells [36]. In the chinchilla, cisplatin predominantly affected outer hair cells and neurons [57], In contrast, carboplatin damaged IHCs, vestibular hair cells and auditory nerves only in chinchillas, and showed little ototoxic potency in other rodents and humans [41, 57, 58]. 

Capsules containing D-glucosamine and chondroitin sulfate are available over the cormter, and many sufferers of osteoarthritis prefer to take this nutritional supplement as an alternative to any nonsteroidal anti-inflammatory drugs (NSAID), such as ibuprofen. Although NSAID can reduce inflammation and pain, long-term use of NSAID can result in stomach ulcers, damage to auditory nerves, and kidney damage. 

Gl disturbances eighth-nerve damage (mainly auditory) renal damage Pentamidine Isethionate... 

Lesions of the nerve and central structures occur due to trauma, tumor growth, and vascular accidents. These maybe subject to surgical intervention to prevent further damage and promote functional recovery. In patients having no auditory nerve due to tumor removal, direct electrical stimulation of the CN has been used to provide auditory sensation. 

Audiologists are concerned with three kinds of hearing loss conductive hearing loss, in which sound waves are not properly transmitted to the inner ear sensorineural hearing loss, in which the cochlea or the auditory nerve is damaged and mixed hearing loss, which is a combination of these. 

Areas of active clinical research development in otorhinolaryngology include cochlear implants, microsurgery, and transplantation. The National Institute on Deafness and Other Communication Disorders is one of the institutions actively involved in auditory research. It sponsors studies that aim to improve the benefits of classical implants as well as efforts to create new hrain-stimulating devices for patients with nerve damage. 

Clark considered the notion that hearing, particularly for speech, might be reproduced in people with deafness if the damaged or underdeveloped ear were bypassed and the auditory nerve electrically stimulated, to reproduce the coding of sound. His initial doctoral research at the University of Sydney investigated the effect of the rate of electrical simulation on single cells and groups of cells in the auditory brainstem response, the centre where frequency discrimination is first decoded. 

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