Ascorbic acid sucrose

Parenteral formulations often contain excipients considered to be chemically stable and inert however, all excipients in a formulation may influence the photochemical stability of the product. Dextrose and sodium chloride are used to adjust tonicity in the majority of parenteral formulations. Sodium chloride can affect photochemical processes by influencing solvation of the photoreactive molecules (see Section 14.2.3). The ionic strength is reported to affect the photochemical decomposition rate of minoxidil until a saturation level is reached (Chinnian and Asker, 1996). The photostability of L-ascorbic acid (vitamin C) in aqueous solution is enhanced in the presence of dextrose, probably caused by the scavenging effect of the excipient on hydroxyl radicals mediated by the photolysis of ascorbic acid sucrose, sorbitol, and mannitol have the same effect (Ho et al., 1994). Monosaccharides (dextrose, glucose, maltose, and lactose), disaccharides (sucrose and trehalose), and polyhydric alcohols (inositol, mannitol, and sorbitol) are examples of commonly used lyo-additives in parenterals. These excipients may also affect photochemical stability of the products after reconstitution. 

Mueller and Bandaranayake [39] were able to show that more than 95% of the following compounds were oxidised in the first run, when present in the water sample at the 5 mg C per litre level oxalic acid, potassium phthalate, humic acid, glucose, sucrose, ascorbic acid, glycine, and phenol. Only sulfur compounds gave incomplete recoveries [58,88]. 

FIG. 8 Effect of 60-min osmotic dehydration at 25 °C at atmospheric pressure in 60% (w/w) sucrose (SU) or sorbitol (SO) solution or 14% (w/w) sucrose (ISO) solution added with 1% ascorbic acid and 0.5% citric acid on drying rates at 70 °C of apricot cubes (NT, not pretreated) (Campolongo, 2002). 

In view of its importance, reductive dissolution of Fe oxides has been widely studied. Reductants investigated include dithionite, thioglycolic acid, thiocyanate, hydrazine, ascorbic acid, hydroquinone, H2S, H2, Fe ", tris (picolinato) V", fulvic acid, fructose, sucrose and biomass/bacteria (Tab. 12.3). Under the appropriate conditions, reductive dissolution may also be effected photochemically. As with protonation, the extent of reduction may be strongly influenced by ligand and proton adsorption on the oxide surface. 

To evaluate the presence of possible interferences, the following metabolites were tested at their physiological concentration bilirubin, sucrose, cholesterol, triglycerides, acetone, urea, uric acid, citric acid, L-ascorbic acid, citrate, pyruvate, haemoglobin, y-globulin, sodium pyruvate, NaCl, KC1, Ca2+ and EDTA. Urea, uric acid, L-ascorbic acid, NaCl, KC1 and Ca2+ generated a slight interference. 

Vitamin C (Ascorbic acid) Chewable Tablets with Sucrose (500 mg)... 

Curl (48), in a study conducted with a synthetic orange juice, reported that the loss of ascorbic acid occurred in the presence of citric acid and potassium citrate buffer alone, but that the losses were increased by the addition of the sugars, levulose, sucrose, and dextrose, in that order. He found that darkening of the synthetic juice occurred principally when both amino acids and sugars were present and, the effect was even more pronounced by the presence of ascorbic acid. 

Composition. Scientific data concerning liquids washed with water from orange juice finisher pulp was first published by Olsen et al. (30). They studied Brix/acid ratios, sucrose, reducing sugars, pH, pectic constituents, turbidity, pulp content, ascorbic acid, viscosity, and flavonoid content of experimental and commercial samples. Characterization of pulp-wash continued with publication of quality data (31), examination of pectic substances (32), microbiology (33), and comparison of pulp-wash with orange concentrate (34). 

It has been found that glucose, sucrose, casein, albumin, sodium chloride, flour groats, and starch stabilize ascorbic acid (vitamin C).771 The addition of 5% of starch inhibits the decomposition of ascorbic acid.772 Studies on the stability of ascorbic acid, sodium ascorbate, erythorbic acid, and sodium erythorbate showed that some stabilization is observed after the addition of 8% starch.773 It was reported that the interaction is purely physical in nature.774... 

Tartaric acid production was accompanied by a process involving recycling of C6 of ascorbic acid into sugars and polysaccharides. When leaves were labeled with l-[ 6-ascorbic acid before anthesis, about 70% of the appeared in soluble (sugar) or residual (polysaccharide) fractions (Table II), a quantity comparable to that found in tartaric acid when the source of label was l-[1- C] ascorbic acid. The bulk of the label in the solution fraction was sucrose, glucose, and fructose while... 

Research the chemical formulas for the following common household items nail polish remover (acetone), vitamin C (ascorbic acid), barbeque charcoal, mothballs (naphthalene), and table sugar (sucrose). ... 

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