Apis mellifera pheromone

Apis mellifera Q-MG Delays worker foraging ontogeny reduces tbeir hemolymph JH titre (2E)-9-Oxodec-2-enoic acid 52, (2 E)-9-hydroxydec-2-enoic acid (71% (R)-(-)) 53, methyl 4-hydroxybenzoate 54, 4-hydroxy-3-methoxyphenylethanol 55 (collectively called queen mandibular pheromone QMP ) [138]... 

Ledoux M. N., Winston M. L., Higo H., Keeling C. I., Slessor K. N. and LeConte Y. (2001) Queen and pheromonal factors influencing comb construction by simulated honey bee (Apis mellifera L.) swarms. Insectes Soc. 48, 14—20. 

Moritz R. F. A., Simon U. E. and Crewe R. M. (2000) Pheromonal contests between honeybee workers (Apis mellifera capensis). Naturwissenschaften 87, 395-397. 

Oldroyd B. P., Ratnieks F. L. W. and Wossler T. C. (2002) Egg-marking pheromones in honeybees Apis mellifera. Behav. Ecol. Sociobiol. 51, 590-591. 

PankiwT. and PageR. E., Jr (2001) Brood pheromone modulates honeybee (Apis mellifera L.) sucrose response thresholds. Behav. Ecol. Sociobiol. 49, 206-213. 

The GOBPs mainly found in the female moth antennae seem to carry odorant molecules found in plant volatiles (Steinbrecht et al., 1995). In the honeybee, Apis mellifera, ASP2 (AmelOBP2) expressed in the antennae of workers and drones can bind odorant molecules of floral scents such as 1,8-cineol, 2-isobutyl-3-methoxypyrazine, 2-heptanone and isoamyl-acetate but do not bind pheromone components (Danty et al., 1997, 1999 Briand et al., 2001). 

Characterization of a chemosensory protein (ASP3c) from honeybee (Apis mellifera L.) as a brood pheromone carrier. Eur. J. Biochem., 269, 4586-4596. 

Despite the importance of such pheromones for the understanding of insect sociality, very little is yet known about them (Le Conte and Hefetz, 2008). So far, in only one species (i.e. the honeybee), has it been shown that a pheromone emitted by a reproductive prevents worker reproduction. In the honeybee, Apis mellifera, it has been suggested that the queen mandibular pheromone (QMP) causes worker ovarian inhibition (Butler and Fairey, 1963). 

Katzav-Gozansky, T., Soroker, V., Ibarra, F., Francke, W. and Hefetz, A. (2001). Dufour s gland secretion of the queen honeybee (Apis mellifera) an egg discriminator pheromone or a queen signal Behav. Ecol. Sociobiol., 51, 76-86. 

Martin, S.J., Chaline, N., Oldroyd, B.P., Jones, G. R. and Ratnieks, F.L.W. (2004a). Egg marking pheromones of anarchistic worker honeybees (Apis mellifera). Behav. Ecol., 15, 839-844. 

Pheromonal dominance and the selection of a socially parasitic honeybee worker lineage (Apis mellifera capensis Esch.)../. Evol. Biol., 20, 997-1007. 

Dietemann, V., Pflugfelder, J., Hartel, S., Neumann, P. and Crewe, R.M. (2006). Social parasitism by honeybee workers (Apis mellifera capensis Esch.) evidence for pheromonal resistance to host queen s signals. Behav. Ecol. Sociobiol., 60, 785-793. 

One of the reported syntheses of ( )-9-oxodec-2-enoic acid 392, the queen substance of the honey bee Apis mellifera, uses two ylide reactions 222). Starting from pimelic acid 385 the resonance-stabilized ylide 386 is prepared by alkylation of methylene-triphenylphosphorane 209 and the former hydrolyzed to 7-oxooctanoic acid 387. Reduction of the corresponding thiol ester 389 and olefination of the resulting aldehyde 390 with phosphorane 67 gives the ( )-2-unsaturated ester 391. The latter was hydrolyzed to pheromone 392 222) (Scheme 69). 

Benton R, Vannice KS, Vosshall LB (2007) An essential role for a CD36-related receptor in pheromone detection in Drosophila. Nature 450 289-293 Blenau W, Baumann A (2001) Molecular and pharmacological properties of insect biogenic amine receptors lessons from Drosophila melanogaster and Apis mellifera. Arch Insect Biochem Physiol 48 13-38... 

Hepburn, H.R. and Radloff, S.E. (1966). Morphometric and pheromonal changes of Apis mellifera L. along a transect from the Sahara to the Pyrenees. Apidologie 7, 35 5. 

Butler, C.G. and Simpson, J. (1967). Pheromones of the queen honey bee (Apis mellifera L.) which enable her workers to follow her when swarming. Proc. Ry. Entomol. Soc. London (A) 42,149-154. 

Pickett, J.A., Williams, I.H., Martin, A.P. and Smith, M.P. (1980). Nasonov pheromone of the honeybee. Apis mellifera L. (Hymenoptera Apidae). Part I. Chemical characterization. /. Chem. Ecol. 6, 426 34. 

Lensky, Y., Gassier P., Rosa, S. and Grandperrin, D. (1991). Induction of balling in worker honeybees Apis mellifera L.) by stress pheromone from Koschewnikow glands of queen bees Behavioral, structural and chemical study. Comp. Biochem. Physiol. IlOA, 585-594. 

Lensky, Y. and Slabezki, Y. (1981). The inhibiting effect of the queen bee (Apis mellifera L.) foot-print pheromone on the construction of swarming queen cups. J. Insect Physiol. 27, 313-323. 

Page, R.E., Blum, M.S. and Fales, H.M. (1988). o-Aminoacetophenone, a pheromone that repels honeybees (Apis mellifera L.). Experientia 44, 270-271. 

Koeniger, N. and Veith, H.J. (1983). Glyceryl-l,2-dioleate-3-palmitate as a brood pheromone of the honey bee (Apis mellifera L.). Experientia 39, 1051-1057. 

The honeybee (Apis mellifera L.) is a social insect. The complex communication network underlying the social organization and behavior of honeybee colonies is primarily governed by pheromones released by the queen, the adult workers, and... 

Slessor KN, Winston ML, Le-Conte Y (2005) Pheromone communication in the honeybee (Apis mellifera L.). J Chem Ecol 31 2731-2745... 

Receptor cells specialized to pheromones have also been studied in other insect groups. In the honey bee. Apis mellifera, two separate cell types have been observed, one for queen substance and another for the alarm pheromone... 

A rich literature exists on the morphology and histology of apoid exocrine glands. Since the honey bee. Apis mellifera, is the best studied of all insects, it is not surprising that more is known about its glands than those of any other bee. Still, Pain (1973) estimates that there may be 31 pheromones in honey bees, of which only 13 had been identified by 1973. Older studies of glandular structure in A. mellifera are summarized in Snodgrass (1956) more recent studies, especially of fine structure, will be cited in this chapter. 

Butler, C. G., Fletcher, D. J. C. and Watler, D. (1969) Nest-entrance marking with pheromones by the honeybee Apis mellifera L., and by a wasp, Vespula vulgaris L. Anim. Behav., 17, 142-7. 

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