Aorta thoracic

Shum-Tim D, Stock U, Hrkach J, Shinoka T, Lien J, Moses MA, Stamp A, Taylor G, Moran A, Landis W, Langer R, Vacanti JP, and Mayer JE Jr. Tissue engineering of autologous aorta using a new biodegradable polymer. Ann Thorac Surg, 1999, 68(6), 2298-304. 

Coronary artery bypass graft surgery Thoracic surgery whereby parts of a saphenous vein from a leg or internal mammary artery from the arm are placed as conduits to restore blood flow between the aorta and one or more coronary arteries to bypass the coronary artery stenosis (occlusion). 

Chen WY, Ko FN, Wu YC, Lu ST, Teng CM. Vasorelaxing effect in rat thoracic aorta caused by laurotetanine isolated from Litsea cubeba Persoon. J Pharm Pharmacol 1994 46 380-382. 

Dimethyl-l,2,5-oxadiazolo[3,4-d]pyridazine 1,5,6-trioxide (41) is also an old product [7,11, 31] that has recently been found to react with GSH to give S-nitrosogluta-thione, NO and HNO [32]. It stimulates partially purified rat lung soluble guanylate cyclase, but not the heme-deficient enzyme. The activation is inhibited by ODQ. The product also displays significant vasodilator activity on rat thoracic aorta rings at nanomolar concentrations. Finally, [l,2,5]oxadiazolo[3,4-d]pyrimidine-5,7-dione 1-oxide derivatives (42, R,Ri=CH3,H) release NO, detected as nitrite, in the presence of thiols. A mechanism for this release has been proposed [33]. 

Studies of apigenin on the rat thoracic aorta have found apigenin to have vasodiiatory effects (Ko et ai. 1991). This effect was probabiy mediated by an inhibition of voitage- and iigand-gated Ca2+ channeis. It wouid be interesting to see if this effect aiso occurs in the CNS. 

Kim KY, McCartney JR, Kaye W, Boland RJ, Niaura R. (1996). The effect of cimetidine and ranitidine on cognitive function in postoperative cardiac surgical patients. Int J Psychiatry Med. 26(3) 295-307. Ko FN, Huang TF, Teng CM. (1991). Vasodilatory action mechanisms of apigenin isolated from Apium graveolens in rat thoracic aorta. Biochim Biophys Acta. 1115(1) 69-74. 

Fig. 4. Records of relaxation of HRW and mixture of the corresponding amino acids (His, Arg and Trp) on 1 juM phenylephrine-contracted thoracic aorta ring from SD rat. PE Phenylephrine (1 juM), ACh Acetylcholine (100 jjM).

Tanaka M, Watanabe S, Wang Z, Matsumoto K, Matsui T. (2009) His-Arg-Trp potently attennates contracted tension of thoracic aorta of Sprague-Dawley rats throngh the snppression of extracellular Ca influx. Peptides 30 1502-1507. 

Tanaka M, Matsni T, Ushida Y, Matsumoto K. (2006) Vasodilating effect of di-peptides in thoracic aortas from spontaneously hypertensive rats. Biosci Biotechnol Biochem 70 2292-2295. 

Tanaka M, Toknyasn M, Matsui T, Matsumoto K. (2008) Endothelium-independent vasodilation effect of di- and tri-peptides in thoracic aorta of Spragne-Dawley rats. Life Sci 82 869-875. 

First level of thoracic vessels Aorta, pulmonary trunk, ductus arteriosus, atria, bronchus, pulmonary vein and arteries, and vena cava (see Note 11). 

Hypolipemic activity. Fiber, administered orally to nine adults with ileostomies at a dose of 13 g/day, increased the excretion of cholesterol " Petroleum ether extract of the fresh fruit, administered to pigs at a concentration of 3.5 g/kg of diet, was inactive "" . Purified green barley extract, in human mononuclear culture of cells isolated from perithelial blood and synovial fluid of patients with rheumatoid arthritis, was active . Leaf essence, administered to atherosclerotic New Zealand White male rabbits at a dose of 1% of diet, produced a decrease of plasma total cholesterol, triacylglycerol, lucigenin-chemilumines-cence, and luminal-chemiluminescence levels. The value of Tj of red blood cell hemolysis and the lag phase of LDL oxidation increased in barley-treated group compared with the control. Ninety percent of the intimal surface of the thoracic aorta was covered with atherosclerotic lesions in the... 

Pharmacokinetics. Seed oil, administered intramuscularly to dogs at a dose of 1 mL/kg labeled glyceryl trioleate injected with the oil, was distributed primarily to iliac nodes, heart, liver, and lungs 5 Phytotoxic effect. Ethanol (95%) extract of the dried seed oil, at a concentration of 500 ppm, was inactive. The biological activity reported has been patented " k Prostaglandin induction. Seed oil, administered subcutaneously to rats at a dose of 1 g/day for 14 days, stimulated PGl-2 synthesis in the thoracic aorta . ... 

Ageel, M. A. A. Nasif, and E. A. Gadkarim. Effects of sesame and cod SI 137 liver oils on prostacyclin synthesis by the rat thoracic aorta. Arch Int Pharmacodyn Ther 1988 292(1) ... 

Incubation in 1-20 iM pyridine for 20 min inhibited norepinephrine-induced phasic and tonic contractions in the thoracic aorta, incubated as aortic rings, as well as the endothelium-denuded aorta of Wistar rats (Hsu Lin-Shiau, 1995). These effects were related to inhibition of the calcium influx normally elicited by norepinephrine. 

Some flavonoids (baicalein, myricetin, quercetagenin and scutellarein) under certain conditions may exert vasoconstrictor rather than vasodilator effects [122]. As described above, myricetin has been shown to exhibit a biphasic response in pre-contracted rat thoracic aorta. At low... 

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