Antigen function

J3. Jessup, J. M., and Thomas, P. C., Carcinoembryonic antigen Function in metastasis by human colorectal carcinoma. Cancer Metastasis Rev. 8, 263-280 (1989). 

Okano, M., Satoskar, A.R., Nishizaki, K. and Harn, D.A. Jr (2001) Lacto-N-fucopentaose III found on Schistosoma mansoni egg antigens functions as adjuvant for proteins by inducing Th2-type response. The Journal of Immunology 1 67, 442-450. 

However, the molecular weight, for example, may vary from 15,000 (hen egg white lysozyme) to 2,000,000 (keyhole limpet hemocyanin) daltons. Protein antigens function as the most potent immunogens, and polysaccharide antigens rank second. For cell-mediated immunity, only proteins serve as immunogens. Certain nucleic acid types such as Z-DNA and other molecules can also stimulate antibody production. 

Scheme 14 Assembly of a reversible immunosensor using a photoisomerizable antigen-functionalized transducer.

Since the photoisomerizable dinitrospiropyran units tethered to the redox enzyme act as photoisomerizable antigen sites for the anti-dinitrophenyl antibody DNP-Ab, the light-controlled association and dissociation of the antibody to and from the antigen-functionalized redox enzyme layer may control the bioelectrocatalytic functions... 

P. M. Kloetzel. Generation of major histocompatibility complex class I antigens functional interplay between proteasomes andTPPII. Nature Immunology, 5 661-669, 2004. 

Marolda, C.L., Vicarioli, J., Valvano, M.A. Wzx proteins involved in biosynthesis of O antigen function in association with the first sugar of the O-specific lipopolysaccharide subunit. Microbiology 150 (2004) 4095 1105. 

The enzymatic back-filling immunoassay model has been demonstrated with the dinitrophenyl antigen-functionalized surface and anti-dinitrophenyl antibody as target analyte... 

Sandrock, A.W. and Matthew, W.D. (1987) An in vitro neu-rite-promoting antigen functions in axonal regeneration in vivo. Science 237 1605-1608. 

Antigen and tumor cell targets Antigen function Naked antibodies Radioisotope-based antibodies Toxin-based antibodies... 

An antigen can in principle exert several types of immunologic functions and it is consistent therefore to regard antigenicity as a broad term comprising all the specialized function. The main antigenic functions may be defined, taking into account earlier published proposals (Sela 1969 Schneider and de Weck 1970 de Weck 1974), as follows ... 

Gell PGH, Harington CR, Rivers RP (1946) The antigenic function of simple chemical compounds production of precipitins in rabbits. Bri J Exp Pathol 27 267... 

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