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Antiallergic oral activity

Cetrizine, 25, is sold as Zyrtec and is widely used as an antiallergic and is most effective against rash/hives. Cetrizine is an orally active racemic compound [11]. [Pg.352]

Tranilast is an orally active antiallergic agent. It may have a similar mechanism of action to that of cromoglicate. [Pg.3479]

The discovery of dlsodlum chromoglycate (DSCG) in 1969 and its unique antiallergic activity ( ) has prompted many laboratories, including our own, to search for more potent, orally active compounds with this activity ( ). We reported in 1976 on a mildly active new series, the pyrantrlones (I) (3 ). [Pg.145]

The chromone cromolyn sodium (5-5) was at one time considered the forerunner of a novel class of antiallergic and antiasthmatic drugs that act at one of the earliest stages of the allergic reaction. Detailed experiments, acmally conducted after the dmg s clinical effectiveness had been confirmed, suggested that the compound inhibited the release of mediators of the allergic reaction from mast cells. The dmg is not very active when taken orally and is usually applied topically to the lung by insufflation as its sodium salt. Considerable efforts to uncover additional structurally related mediator release inhibitors have had only limited success. [Pg.432]

A -cortisol prednisolone, cortisone (ban. inn] (cortisone acetate [usan] Kendall s compound E Reichstein s Substance Fa Wintersteiner s compound F NSC 9703 Cortisyl ) is a natural adrenal cortical hormone, a CORTICOSTEROID, which is converted to hydrocortisone in the liver. It has both GLUCOCORTICOID and MINERALOCORTICOID activity. It can therefore be used orally to make up for hormonal deficiency (especially mineral balance), for instance, following surgical removal of the adrenal glands. It can also be used for its ANTIINFLAMMATORY and ANTIALLERGIC properties in treating rheumatoid arthritis and in rheumatic fever therapy, cortisone acetate cortisone. [Pg.85]


See other pages where Antiallergic oral activity is mentioned: [Pg.176]    [Pg.150]    [Pg.447]    [Pg.285]    [Pg.243]    [Pg.63]    [Pg.176]    [Pg.176]    [Pg.179]    [Pg.51]    [Pg.596]    [Pg.1]    [Pg.6]    [Pg.8]    [Pg.10]    [Pg.13]    [Pg.142]    [Pg.294]    [Pg.176]    [Pg.255]    [Pg.34]    [Pg.328]    [Pg.245]    [Pg.246]    [Pg.255]    [Pg.271]    [Pg.255]    [Pg.3182]    [Pg.1980]    [Pg.177]    [Pg.15]    [Pg.71]    [Pg.72]    [Pg.86]    [Pg.98]    [Pg.124]    [Pg.145]    [Pg.190]    [Pg.212]    [Pg.271]    [Pg.571]    [Pg.594]    [Pg.272]    [Pg.255]    [Pg.1871]   
See also in sourсe #XX -- [ Pg.7 , Pg.8 , Pg.9 ]




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Antiallergics

Oral activity

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