Monobasic sodium phosphate anhydrous

Anhydrous monobasic sodium phosphate [7558-80-7] Monobasic sodium phosphate monohydrate [10049-21-5] Monobasic sodium phosphate dihydrate [13472-35-0]... 

One gram of anhydrous monobasic sodium phosphate represents approximately 8.3 mmol of sodium and of phosphate. 

Each Imitrex Nasal Spray contains 5 or 20 mg of sumatriptan in a 100-pL unit-dose aqueous buffered solution containing monobasic potassium phosphate, anhydrous dibasic sodium phosphate, sulfuric acid, sodium hydroxide,... 

Per Redipen 1.013 mg dibasic sodium phosphate anhydrous 1.013 mg monobasic sodium phosphate dehydrate 54 mg sucrose 0.0675 mg polysorbate 80... 

Phosphate buffer Dissolve 0.725 g of monobasic sodium phosphate and 4.472 g of anhydrous dibasic sodium phosphate in 300 ml of water, dilute with water to 1000 ml, and mix. Dilute 250 ml of this solution with water to 1000 ml. If necessary, adjust the pH with phosphoric acid to 7.6. 

M Phosphate Buffer (pH 7.0) Dissolve 4.54 g of monobasic potassium phosphate in water, and dilute to 500 mL. Dissolve 4.73 g of anhydrous dibasic sodium phosphate in water, and dilute to 500 mL. Mix 38.0 mL of the monobasic potassium phosphate solution with 61.1 mL of the dibasic sodium phosphate solution. Adjust the pH of the mixture to 7.0 by the dropwise addition of the dibasic sodium phosphate solution, if necessary. 

Mix 13 mL of the monobasic potassium phosphate solution with 87 mL of the anhydrous dibasic sodium phosphate solution. 

Monobasic Sodium Phosphate is anhydrous or contains one or two molecules of water of hydration and is slightly hygroscopic. The anhydrous form occurs as a white, crystalline powder or granules. The hydrated forms occur as white or transparent crystals or granules. All forms are freely soluble in water, but are insoluble in alcohol. The pH of a 1 100 solution is between 4.1 and 4.7. 

The USP 28 states that monobasic sodium phosphate contains one or two molecules of water of hydration or is anhydrous. 

The hydrated forms of monobasic sodium phosphate occur as odorless, colorless or white, slightly deliquescent crystals. The anhydrous form occurs as a white crystalline powder or granules. 

Each vial contains either 74, 118.4, 177.6, or 222 p.g of PEG-intron, and 1.11 mg of dibasic sodium phosphate anhydrous, 1.11 mg of monobasic sodium phosphate dihydrate, 59.2 mg of sucrose, and 0.074 mg of polysorbate 80. Following reconstitution with 0.7 mL of the supplied diluent (SWFI, USP), each vial contains peginterferon at strengths of either 100, 160, 240, or 300 p,g/mL. 

M NaCl. To 900 mL of deionized water, add 0.53 g of monobasic sodium phosphate monohydrate (NaH2P04-H20) and 0.87 g of dibasic sodium phosphate anhydrous (Na2HP04). Add 8.77 g of sodium chloride (NaCl) and dilute to a final volume of 1,000 mL with deionized water. 

Phosphate-buffered saline (PBS), pH 7.4 8 g sodium chloride (NaCl), 200 mg potassium chloride (KC1), 200 mg monobasic potassium phosphate (KH2P04), 1.15 g anhydrous dibasic sodium phosphate (Na2HP04), bring volume to 1 L with deionized glass-distilled water (dH20). 

In addition, each package consisting of five labeling units contains also five vials of methylene blue injection 1% USP (10 mg methylene blue USP in 1 ml water for injection), and five vials containing 0.003 M monobasic sodium phosphate USP and dibasic sodium phosphate USP in 4.5 ml of 0.9% sodium chloride injection USP. Each milliliter contains 0.276 mg monobasic sodium phosphate monohydrate, 0.142 mg dibasic sodium phosphate anhydrous, and 9 mg sodium chloride in water for injection for a sufficient amount. A mixture of methylene blue in phosphate buffer is used for stabilization of the Tc-HMPAO complex (Amersham Healthcare 1995). 

Fleat 75% of the water to 70°C in a suitable vessel. Add the monobasic sodium phosphate monohydrate, anhydrous dibasic sodium phosphate, propylene glycol, and benzyl alcohol to the vessel with agitation, maintaining the temperature at 70°C. 

Phosphate-buffered saline (PBS) without divalent cations 1.50 g/L dibasic sodium phosphate (Na2HP04-7H20), 0.2 g/L anhydrous monobasic potassium phosphate (KH2PO4), 8 g/L sodium chloride (NaCl), and 0.2 g/L potassium chloride (KCl), pH to 7.4. 

Avastin Avastin is used for the treatment of colorectal cancer. It is supplied in 100 and 400 mg dosages. The 100 mg formulation consists of 240 mg a,a-trehalose dihydrate, 23.2 mg sodium phosphate (monobasic, monohydrate), 4.8mg sodium phosphate (dibasic, anhydrous), 1.6mg polysorbate 20 and water-for-injection. 

PEG-Intron PEG-Intron is used for the treatment of hepatitis C. The product consists of a covalent conjugate of the recombinant interferon- -2b with monomethoxy polyethylene glycol (PEG) supplied in vials with 74/rg, 118.4/rg, 177.6/rg, or 222/rg of the active ingredient and 1.11 mg sodium phosphate (dibasic,anhydrous),l.ll mg sodium phosphate (monobasic, dihydrate), 59.2 mg sucrose, and 0.074mg polysorbate 80. The powder is reconstituted with sterile water-for-injection. 

Formulation Aranesp is formulated as a sterile, colorless, preservative-free protein solution for intravenous (IV) or subcutaneous (SC) administration. There are two formulations the polysorbate solution includes excipients such as polysorbate 80, sodium phosphate monobasic monohydrate, sodium phosphate dibasic anhydrous, and sodium chloride in water-for-injection while the albumin solution contains albumin, sodium phosphate monobasic monohydrate, sodium phosphate dibasic anhydrous, and sodium chloride in water-for-injection. The pH for both formulations is 6.2 + 0.2. 

A new formulation of a saline laxative, Visicol, that is useful to prepare patients for procedures, was approved for use in 2001. Each 2-g tablet contains 1.102 g sodium phosphate monobasic monohydrate and 0.398 g sodium phosphate dibasic anhydrous, for a total of 1.5 g sodium phosphate. Visicol tablets, taken in two doses of 30 g approximately 12 hours apart, induce diarrhea that rapidly and effectively cleanses the entire colon. Each administration has a purgative effect for approximately 1 to 3 hours. 

Per 1 mL 2.5 mg albumin (human) 1.2 mg sodium phosphate monobasic monohydrate 1.8 mg sodium phosphate dibasic anhydrate 0.7 mg sodium citrate 5.8 mg sodium chloride 6.8 pg citric acid in WFI, USP... 

Per 1 mL polysorbate solution 0.05mg/mL polysorbate 80 2.12mg/mL sodium phosphate monobasic monohydrate 0.66mg/mL sodium phosphate dibasic anhydrous 8.18mg/mL sodium chloride (pH 6.2 0.2)... 

Per 20 mg vial 7.21 mg monobasic potassium phosphate 0.99 mg disodium hydrogen phosphate (anhydrous) 1.61 mg sodium chloride 20 mg sucrose 80 mg mannitol 40 mg glycine... 

Per 1 mL 1.36 mg glycine 36.0 mg mannitol 1.04mg sodium phosphate dibasic anhydrous 0.36 mg sodium phosphate monobasic monohydrate... 

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