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Angiogenesis chemokines

Sahn SA. Malignancy metastatic to the pleura. Clin Chest Med 1998 19 351-361. Negus RPM, Balkwill FR. Chemokines and gynecologic malignancies. In Chemo-kines and Cancer, BJ Rollins, ed. Totowa, NJ Humana Press 1999 193-205. Stricter RM, DiGiovine B, Polverini PJ, et al. C-X-C chemokines and lung cancer angiogenesis. Chemokines Cancer 1999 143-167. [Pg.338]

Rempel SA, Dudas S, Ge S, Gutierrez JA (2000) Identification and localization of the cytokine SDFl and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma. Chn Cancer Res 6 102-111 Reya T, Morrison SJ, Clarke ME, Weissman IL (2001) Stem cells, cancer, and cancer stem cells. Nature 414 105-111... [Pg.269]

Koch AE, Volin MV, Woods JM, et al. Regulation of angiogenesis by the C-X-C chemokines interleukin-8 and epithelial neutrophil activating peptide 78 in the rheumatoid joint. Arthritis Rheum 2001 44(1) 31 40. [Pg.194]

Key Words Chemokine chemokine receptor angiogenesis inflammation fibrosis cancer. [Pg.319]

The CXC chemokines can be divided into two groups on the basis of a structure/function domain consisting of the presence or absence of three amino acid residues (Glu-Leu-Arg ELR motif) that precedes the first cysteine amino acid residue in the primary structure of these cytokines. The ELR+ CXC chemokines are chemoattractants for neutrophils and act as potent angiogenic factors (6). In contrast, the ELR" CXC chemokines are chemoattractants for mononuclear cells and are potent inhibitors of angiogenesis (Table 1) (6). [Pg.321]

Based on the structural/functional difference, the members of the CXC chemokine family are unique cytokines in their ability to behave in a disparate manner in the regulation of angiogenesis. The angiogenic members include... [Pg.321]

CXCR2 Is the Receptor for Angiogenic ELR+ CXC Chemokine-Mediated Angiogenesis... [Pg.322]

CXCR3 Appears to Be the Major Receptor for CXC Chemokines That Inhibit Angiogenesis... [Pg.325]

Strieter RM, Polverini PJ, Kunkel SL, et al. The functional role of the ELR motif in CXC chemokine-mediated angiogenesis. J Biol Chem 1995 270(45) 27348-27357. [Pg.329]

Salcedo R, Oppenheim JJ. Role of chemokines in angiogenesis CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses. Microcirculation 2003 10(3-4) 359-370. [Pg.332]

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See also in sourсe #XX -- [ Pg.18 ]



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